Immune therapies for autoimmune diabetes targeting pathogenic peptide–MHC complexes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Cell Biology"
DOI: 10.1093/jmcb/mjaa037
Abstract: At present, there is no cure for type 1A diabetes (T1D), a T cell-mediated autoimmune disease. Monoclonal antibodies (mAbs) are used to treat a wide number of diseases. For treating T1D, mAbs that target major… read more here.
Keywords: mhc complexes; peptide mhc; therapies autoimmune; disease ... See more keywords
Experimental Structures of Antibody/MHC-I Complexes Reveal Details of Epitopes Overlooked by Computational Prediction.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of immunology"
DOI: 10.4049/jimmunol.2300839
Abstract: mAbs to MHC class I (MHC-I) molecules have proved to be crucial reagents for tissue typing and fundamental studies of immune recognition. To augment our understanding of epitopic sites seen by a set of anti-MHC-I… read more here.
Keywords: antibody mhc; structures antibody; mhc complexes; anti mhc ... See more keywords