Massive introgression of MHC genes in newt hybrid zones.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular ecology"
DOI: 10.1111/mec.15254
Abstract: Variation in the vertebrate major histocompatibility complex (MHC) genes is crucial for fighting pathogen assault. Because new alleles confer a selective advantage, MHC should readily introgress between species, even under limited hybridization. Using replicated transects… read more here.
Keywords: mhc genes; introgression; massive introgression; mhc ... See more keywords
Interspecific introgression of MHC genes in Triturus newts: Evidence from multiple contact zones
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Ecology"
DOI: 10.1111/mec.16804
Abstract: The major histocompatibility complex (MHC) genes are central to the adaptive immune response in vertebrates. Selection generally maintains high MHC variation because the spectrum of recognized pathogens depends on MHC polymorphism. Novel alleles favoured by… read more here.
Keywords: mhc; introgression; mhc introgression; mhc genes ... See more keywords
Widespread introgression of MHC genes in Iberian Podarcis lizards.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular ecology"
DOI: 10.1111/mec.16974
Abstract: Major histocompatibility complex (MHC) genes are crucial for the adaptive immune response of jawed vertebrates. Their variation, reaching extreme levels, is driven mainly by an arms race between hosts and pathogens. One hypothesised mechanism contributing… read more here.
Keywords: podarcis lizards; mhc; introgression; adaptive introgression ... See more keywords
Characterization of two MHC II genes (DOB, DRB) in white-tailed deer (Odocoileus virginianus)
Sign Up to like & getrecommendations! Published in 2020 at "BMC Genetics"
DOI: 10.1186/s12863-020-00889-5
Abstract: The major histocompatibility complex (MHC) is responsible for detecting and addressing foreign pathogens inside the body. While the general structure of MHC genes is relatively well conserved among mammalian species, it is notably different among… read more here.
Keywords: white tailed; tailed deer; mhc drb; mhc genes ... See more keywords
Wild Boar (Sus scrofa)—Fascioloides magna Interaction from the Perspective of the MHC Genes
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11111359
Abstract: Fascioloidosis is a parasitic disease caused by a trematode Fascioloides magna. Since major histocompatibility complex (MHC) genes play an important role in the immune response, the aim of this study was to compare the potential… read more here.
Keywords: fascioloides magna; mhc genes; sla; sla drb1 ... See more keywords