Structure-based prediction of T cell receptor:peptide-MHC interactions
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.08.05.503004
Abstract: The regulatory and effector functions of T cells are initiated by the binding of their cell-surface T cell receptor (TCR) to peptides presented by major histocompatibility complex (MHC) proteins on other cells. The specificity of… read more here.
Keywords: tcr peptide; prediction; mhc interactions; cell receptor ... See more keywords
Trans-Allelic Model for Prediction of Peptide:MHC-II Interactions
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.01410
Abstract: Major histocompatibility complex class two (MHC-II) molecules are trans-membrane proteins and key components of the cellular immune system. Upon recognition of foreign peptides expressed on the MHC-II binding groove, CD4+ T cells mount an immune… read more here.
Keywords: mhc interactions; peptide mhc; trans allelic; model ... See more keywords