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Published in 2020 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2020.03.183
Abstract: Background & Aim Mesenchymal stromal cells (MSCs) are of clinical interest because of their validated safety profile and their tremendous biological properties. Nonetheless, variable clinical outcomes have been reported in the literature. Non-reproducible results are…
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Keywords:
mhci;
novel cell;
cell based;
expression levels ... See more keywords
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Published in 2018 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1006883
Abstract: Viruses have evolved mechanisms of MHCI inhibition in order to evade recognition by cytotoxic CD8+ T cells (CTLs), which is well-illustrated by our prior studies on cowpox virus (CPXV) that encodes potent MHCI inhibitors. Deletion…
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Keywords:
cpxv;
immunodomination;
inhibition;
mhci ... See more keywords