A novel cell-based strategy based on MHCI/CD90 expression levels for highly proliferative MSC identification
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DOI: 10.1016/j.jcyt.2020.03.183
Abstract: Background & Aim Mesenchymal stromal cells (MSCs) are of clinical interest because of their validated safety profile and their tremendous biological properties. Nonetheless, variable clinical outcomes have been reported in the literature. Non-reproducible results are… read more here.
Keywords: mhci; novel cell; cell based; expression levels ... See more keywords
Cross-priming induces immunodomination in the presence of viral MHC class I inhibition
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DOI: 10.1371/journal.ppat.1006883
Abstract: Viruses have evolved mechanisms of MHCI inhibition in order to evade recognition by cytotoxic CD8+ T cells (CTLs), which is well-illustrated by our prior studies on cowpox virus (CPXV) that encodes potent MHCI inhibitors. Deletion… read more here.
Keywords: cpxv; immunodomination; inhibition; mhci ... See more keywords