Articles with "mhcii restricted" as a keyword



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Antigen discovery and specification of immunodominance hierarchies for MHCII-restricted epitopes

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Published in 2018 at "Nature Medicine"

DOI: 10.1038/s41591-018-0203-7

Abstract: Identifying immunodominant T cell epitopes remains a significant challenge in the context of infectious disease, autoimmunity, and immuno-oncology. To address the challenge of antigen discovery, we developed a quantitative proteomic approach that enabled unbiased identification… read more here.

Keywords: antigen discovery; immunodominance; restricted epitopes; cell ... See more keywords