Toxicity, Pharmacokinetics, and Gut Microbiome of Oral Administration of Sesterterpene MHO7 Derived from a Marine Fungus
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DOI: 10.3390/md17120667
Abstract: Sesterterpene MHO7 derived from mangrove fungus is a novel estrogen receptor degrader for the treatment of breast cancer. To explore its safety and pharmacokinetics in vivo, Log P/D values, stability in simulated gastric/intestinal (SGF/SIF), toxicity,… read more here.
Keywords: mho7 derived; administration; toxicity pharmacokinetics; sesterterpene mho7 ... See more keywords