Articles with "mhtt protein" as a keyword



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Ubiquitin-modifying enzymes in Huntington’s disease

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Published in 2023 at "Frontiers in Molecular Biosciences"

DOI: 10.3389/fmolb.2023.1107323

Abstract: Huntington’s disease (HD) is a neurodegenerative disorder caused by a CAG repeat expansion in the N-terminus of the HTT gene. The CAG repeat expansion translates into a polyglutamine expansion in the mutant HTT (mHTT) protein,… read more here.

Keywords: huntington disease; ubiquitin modifying; modifying enzymes; expansion ... See more keywords