Current Consensus on I-131 MIBG Therapy
Sign Up to like & getrecommendations! Published in 2018 at "Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s13139-018-0523-z
Abstract: Metaiodobenzylguanidine (MIBG) is structurally similar to the neurotransmitter norepinephrine and specifically targets neuroendocrine cells including some neuroendocrine tumors. Iodine-131 (I-131)-labeled MIBG (I-131 MIBG) therapy for neuroendocrine tumors has been performed for more than a quarter-century.… read more here.
Keywords: unresectable metastatic; 131 mibg; mibg therapy; mibg ... See more keywords
Association of plasma α-synuclein with cardiac 123I-MIBG scintigraphy in early Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2021.136399
Abstract: Cardiac 123I-metaiodobenzylguanidine (MIBG) uptake correlates with the extent of cardiac sympathetic denervation found in disease with Lewy pathology, such as Parkinson's disease (PD). Protein α-synuclein, the main component of Lewy body, is a candidate biomarker… read more here.
Keywords: mibg; synuclein; parkinson disease; plasma synuclein ... See more keywords
Evaluating the diagnostic efficacy of whole-body MRI versus 123I-mIBG/131I-mIBG imaging in metastatic pheochromocytoma and paraganglioma
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DOI: 10.1038/s41598-024-64607-2
Abstract: This study aimed to compare tumor lesion detectability and diagnostic accuracy of whole-body magnetic resonance imaging (WB-MRI) and radioiodine-labeled meta-iodo-benzylguanidine (mIBG) imaging techniques in patients with metastatic pheochromocytoma and paraganglioma (PPGL). This retrospective study included… read more here.
Keywords: 123i mibg; mibg; mibg images; pheochromocytoma paraganglioma ... See more keywords
Recent Advances in Radiopharmaceutical Theranostics of Pheochromocytoma and Paraganglioma.
Sign Up to like & getrecommendations! Published in 2023 at "Seminars in nuclear medicine"
DOI: 10.1053/j.semnuclmed.2022.12.005
Abstract: As a rare kind of non-epithelial neuroendocrine neoplasms, paragangliomas (PGLs) exhibit various clinical characteristics with excessive catecholamine secretion and have been a research focus in recent years. Although several modalities are available nowadays, radiopharmaceuticals play… read more here.
Keywords: theranostics pheochromocytoma; pheochromocytoma paraganglioma; advances radiopharmaceutical; mibg ... See more keywords
131 I-mIBG Therapy in the Management of High-Risk Neuroblastoma: A Retrospective Study from a Tertiary Level Hospital in South India
Sign Up to like & getrecommendations! Published in 2024 at "Indian Journal of Medical and Paediatric Oncology"
DOI: 10.1055/s-0044-1787303
Abstract: Abstract Introduction Neuroblastoma is the most common extracranial solid tumor in childhood. The data on the treatment experience with 131 iodine-meta-iodo-benzyl-guanidine ( 131 I-mIBG) and clinical outcome data are meager from India. Objectives This article… read more here.
Keywords: risk neuroblastoma; 131 mibg; therapy; mibg ... See more keywords
P3559Renal sympathetic nerve activity, assessed by renal 123-iodine metaiodobenzylguanidine scintigraphy, reflects disease severity in heart failure with reduced ejection fraction
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz745.0422
Abstract: Sympathetic nerve activity is related to cardio-renal syndrome, which plays a crucial role in deterioration in heart failure with reduced ejection fraction (HFrEF). Previous studies reported that renal denervation was effective in HFrEF patients. Recently,… read more here.
Keywords: heart; heart failure; mibg; nerve activity ... See more keywords
The utility of the combination of a SPECT study with [123I]-FP-CIT of dopamine transporters and [123I]-MIBG myocardial scintigraphy in differentiating Parkinson disease from other degenerative parkinsonian syndromes
Sign Up to like & getrecommendations! Published in 2017 at "Nuclear Medicine Communications"
DOI: 10.1097/mnm.0000000000000674
Abstract: Objective Molecular imaging of nigrostriatal dopamine transporters (DAT) and sympathetic cardiac innervation with single-photon emission computed tomography (SPECT) are useful tools for differentiating idiopathic Parkinson disease (PD) from other degenerative parkinsonian syndromes (non-PD). Nevertheless, these… read more here.
Keywords: combination; scintigraphy; spect; accuracy ... See more keywords
Functional Imaging Evidence of Tumor Response to High-Specific-Activity 131I-MIBG Therapy in an 84-Year-Old Patient With Metastatic Pheochromocytoma/Paraganglioma.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000004519
Abstract: ABSTRACT An 84-year-old man with history of metastatic pheochromocytoma/paraganglioma (mPPGL) received surgery 13 years ago, with recent biopsy-proven mPPGL in the T11. 123I-MIBG scan showed MIBG-avid liver and osseous. Given his medical condition and body… read more here.
Keywords: pheochromocytoma paraganglioma; metastatic pheochromocytoma; year old; patient ... See more keywords
Concurrent Intracranial and Spinal Dural Metastases Demonstrated by 68Ga-DOTATATE PET/CT With Negative 123I-MIBG SPECT/CT in a Pediatric Neuroblastoma Patient.
Sign Up to like & getrecommendations! Published in 2024 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000005448
Abstract: ABSTRACT Contrast enhancement MRI of the brain and spine showed abnormal enhancement in intracranial and spinal dural lesions in a 6-year-old boy with high-risk neuroblastoma, suggesting the possibility of dural metastases. 123I-MIBG SPECT/CT did not… read more here.
Keywords: 123i mibg; dural metastases; spinal dural; intracranial spinal ... See more keywords
Clinical Applications and the Roles of Transporters in Disposition, Tumor Targeting, and Tissue Toxicity of meta-Iodobenzylguanidine
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DOI: 10.1124/dmd.121.000707
Abstract: Transporters on the plasma membrane of tumor cells are promising molecular “Trojan horses” to deliver drugs and imaging agents into cancer cells. Radioiodine-labeled meta-iodobenzylguanidine (mIBG) is used as a diagnostic agent (123I-mIBG) and a targeted… read more here.
Keywords: disposition; meta iodobenzylguanidine; normal tissues; mibg ... See more keywords
Integrated Imaging Characterization of Adrenal Adenoma: False-Positive Metaiodobenzylguanidine (MIBG) Findings of Adrenal Scintigraphy
Sign Up to like & getrecommendations! Published in 2017 at "Polish Journal of Radiology"
DOI: 10.12659/pjr.901853
Abstract: Summary Background Evaluation of a patient with melanoma in whom an adrenal mass was detected on CT and MR during follow-up and further characterized with PET-CT and MIBG scintigraphy. Case Report In this case report,… read more here.
Keywords: integrated imaging; scintigraphy; imaging characterization; adrenal adenoma ... See more keywords