Multiplexed Ion Beam Imaging Readout of Single-Cell Immunoblotting.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c01050
Abstract: Improvements in single-cell protein analysis are required to study the cell-to-cell variation inherent to diseases, including cancer. Single-cell immunoblotting (scIB) offers proteoform detection specificity, but often relies on fluorescence-based readout and is therefore limited in… read more here.
Keywords: single cell; protein; mibi tof; cell immunoblotting ... See more keywords
The immunoregulatory landscape of human tuberculosis granulomas
Sign Up to like & getrecommendations! Published in 2022 at "Nature Immunology"
DOI: 10.1038/s41590-021-01121-x
Abstract: Tuberculosis (TB) in humans is characterized by formation of immune-rich granulomas in infected tissues, the architecture and composition of which are thought to affect disease outcome. However, our understanding of the spatial relationships that control… read more here.
Keywords: immunoregulatory landscape; human tuberculosis; tuberculosis; granulomas ... See more keywords