869: VANCOMYCIN TROUGHS CAN PREDICT AUC/MIC RATIOS OF 400-600 IN CRITICALLY ILL PATIENTS
Sign Up to like & getrecommendations! Published in 2020 at "Critical Care Medicine"
DOI: 10.1097/01.ccm.0000631612.17905.d2
Abstract: Introduction/Hypothesis: The efficacy of vancomycin has historically been associated with a defined trough concentration range. Accumulating evidence indicates vancomycin efficacy is more strongly associated with the achievement of a 24 hour area under the curve/minimum… read more here.
Keywords: mic ratio; 400 600; auc24 mic; trough concentration ... See more keywords
Evaluation of Therapeutic Vancomycin Monitoring in Taiwan
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DOI: 10.1128/spectrum.01562-21
Abstract: Since 2020, the Infectious Diseases Society of America (IDSA) updated vancomycin guidelines, and vancomycin AUC therapeutic drug monitor was updated to AUC/MIC in the United States. But acceptable rate of infection physicians in Taiwan was… read more here.
Keywords: taiwan; vancomycin; monitoring; auc mic ... See more keywords
Pharmacokinetic/Pharmacodynamic Target Attainment of Vancomycin, at Three Reported Infusion Modes, for Methicillin-Resistant Staphylococcus aureus (MRSA) Bloodstream Infections in Critically Ill Patients: Focus on Novel Infusion Mode
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.874401
Abstract: Objective The study aimed to evaluate and compare the pharmacokinetic/pharmacodynamic (PK/PD) exposure to vancomycin in the novel optimal two-step infusion (OTSI) vs. intermittent infusion (II) vs. continuous infusion (CI) mode, for MRSA bloodstream infections occurring… read more here.
Keywords: mic ratio; pta auc0; 400 600; infusion ... See more keywords
Bactericidal Activity of Sodium Bituminosulfonate against Staphylococcus aureus
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DOI: 10.3390/antibiotics11070896
Abstract: Antibiotic resistance is increasing worldwide making it necessary to search for alternative antimicrobials. Sodium bituminosulfonate is a long-known substance, whose antimicrobial inhibitory activity has recently been re-evaluated. However, to the best of our knowledge, the… read more here.
Keywords: sodium bituminosulfonate; mbc mic; bituminosulfonate; mic ratio ... See more keywords