Mitochondrial inner membrane protein, Mic60/mitofilin in mammalian organ protection
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27314
Abstract: The identification of the mitochondrial contact site and cristae organizing system (MICOS) in the inner mitochondrial membrane shed light on the intricate components necessary for mitochondria to form their signature cristae in which many protein… read more here.
Keywords: protein; mitochondrial inner; mic60; membrane ... See more keywords
Loss of MIC60 Aggravates Neuronal Death by Inducing Mitochondrial Dysfunction in a Rat Model of Intracerebral Hemorrhage.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular neurobiology"
DOI: 10.1007/s12035-021-02468-w
Abstract: Mitochondrial damage has been reported to be a critical factor for secondary brain injury (SBI) induced by intracerebral hemorrhage (ICH). MIC60 is a key element of the mitochondrial contact site and cristae junction organizing system… read more here.
Keywords: ich induced; neuronal death; intracerebral hemorrhage; mic60 ... See more keywords
Mic60 is essential to maintain mitochondrial integrity and to prevent encephalomyopathy.
Sign Up to like & getrecommendations! Published in 2023 at "Brain pathology"
DOI: 10.1111/bpa.13157
Abstract: Mitochondrial encephalomyopathies (ME) are frequently associated with mutations of mitochondrial DNA, but the pathogenesis of a subset of ME (sME) remains elusive. Here we report that haploinsufficiency of a mitochondrial inner membrane protein, Mic60, causes… read more here.
Keywords: mic60; essential maintain; mic60 essential; maintain mitochondrial ... See more keywords