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   Articles with "mic60" as a keyword



Mitochondrial inner membrane protein, Mic60/mitofilin in mammalian organ protection

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recommendations! Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.27314

Abstract: The identification of the mitochondrial contact site and cristae organizing system (MICOS) in the inner mitochondrial membrane shed light on the intricate components necessary for mitochondria to form their signature cristae in which many protein… read more here.

Keywords: protein; mitochondrial inner; mic60; membrane ... See more keywords

Loss of MIC60 Aggravates Neuronal Death by Inducing Mitochondrial Dysfunction in a Rat Model of Intracerebral Hemorrhage.

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recommendations! Published in 2021 at "Molecular neurobiology"

DOI: 10.1007/s12035-021-02468-w

Abstract: Mitochondrial damage has been reported to be a critical factor for secondary brain injury (SBI) induced by intracerebral hemorrhage (ICH). MIC60 is a key element of the mitochondrial contact site and cristae junction organizing system… read more here.

Keywords: ich induced; neuronal death; intracerebral hemorrhage; mic60 ... See more keywords

The Core MICOS Complex Subunit mic60 has Been Substituted by Two Cryptic Mitofilin-containing Proteins in Euglenozoa

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recommendations! Published in 2025 at "Molecular Biology and Evolution"

DOI: 10.1093/molbev/msaf289

Abstract: Cristae enclose respiratory chain complexes, making them the bioenergetic subcompartments of mitochondria. The MICOS complex is among the inducers of membrane curvature needed for crista formation. Resembling the respiratory chain complexes, MICOS is organized around… read more here.

Keywords: mitofilin; core; two cryptic; mic60 ... See more keywords

Mic60 is essential to maintain mitochondrial integrity and to prevent encephalomyopathy.

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recommendations! Published in 2023 at "Brain pathology"

DOI: 10.1111/bpa.13157

Abstract: Mitochondrial encephalomyopathies (ME) are frequently associated with mutations of mitochondrial DNA, but the pathogenesis of a subset of ME (sME) remains elusive. Here we report that haploinsufficiency of a mitochondrial inner membrane protein, Mic60, causes… read more here.

Keywords: mic60; essential maintain; mic60 essential; maintain mitochondrial ... See more keywords