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   Articles with "mical2" as a keyword



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Enriching the Arsenal of Pharmacological Tools against MICAL2

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recommendations! Published in 2021 at "Molecules"

DOI: 10.3390/molecules26247519

Abstract: Molecule interacting with CasL 2 (MICAL2), a cytoskeleton dynamics regulator, are strongly expressed in several human cancer types, especially at the invasive front, in metastasizing cancer cells and in the neo-angiogenic vasculature. Although a plethora… read more here.

Keywords: pharmacological tools; mical2; enriching arsenal; ccg 1423 ... See more keywords
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lnc‑MICAL2‑1 sponges miR‑25 to regulate DKK3 expression and inhibits activation of the Wnt/β‑catenin signaling pathway in breast cancer.

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recommendations! Published in 2022 at "International journal of molecular medicine"

DOI: 10.3892/ijmm.2021.5078

Abstract: The Dickkopf 3 (DKK3) protein antagonizes the Wnt receptor complex in the Wnt signaling pathway; however, to date, there have been no relevant studies investigating its upstream regulatory mechanism in breast cancer (BC), to the best… read more here.

Keywords: lnc mical2; dkk3 expression; signaling pathway; mical2 ... See more keywords
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Overexpression of MICAL2, a novel tumor-promoting factor, accelerates tumor progression through regulating cell proliferation and EMT

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recommendations! Published in 2018 at "Journal of Cancer"

DOI: 10.7150/jca.22355

Abstract: Molecule interacting with CasL 2 (MICAL2), a microtubule associated monooxygenase, is involved in cell growth, axon guidance, vesicle trafficking and apoptosis. Recent studies have demonstrated that MICAL2 is highly expressed in tumor and accelerates tumor… read more here.

Keywords: tumor progression; mical2; factor; cell ... See more keywords
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MICAL2 Mediates p53 Ubiquitin Degradation through Oxidating p53 Methionine 40 and 160 and Promotes Colorectal Cancer Malignance

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recommendations! Published in 2018 at "Theranostics"

DOI: 10.7150/thno.28228

Abstract: Molecule interacting with CasL2 (MICAL2), a microtubule-associated monooxygenase, is highly expressed in various cancers and is involved in cancer pathogenesis, but the mechanisms underlying its regulation in carcinogenesis are unclear. In this study, we aim… read more here.

Keywords: mical2; ubiquitin degradation; crc; cancer ... See more keywords