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Published in 2017 at "Epilepsia Open"
DOI: 10.1002/epi4.12031
Abstract: C57BL/6J mice exposed to eight flurothyl‐induced generalized clonic seizures exhibit a change in seizure phenotype following a 28‐day incubation period and subsequent flurothyl rechallenge. Mice now develop a complex seizure semiology originating in the forebrain…
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Keywords:
eight flurothyl;
brainstem seizure;
flurothyl induced;
exposed eight ... See more keywords
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Published in 2020 at "Archives of Toxicology"
DOI: 10.1007/s00204-020-02785-4
Abstract: 1,2-Dichloropropane (1,2-DCP) is recognized as the causative agent for cholangiocarcinoma among offset color proof-printing workers in Japan. The aim of the present study was to characterize the molecular mechanisms of 1,2-DCP-induced hepatotoxic effects by proteomic…
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Keywords:
proteins mice;
analysis;
mice exposed;
proteomic analysis ... See more keywords
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Published in 2017 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2016.12.001
Abstract: Prenatal maternal infection represents a risk factor for the development of psychopathologic conditions later in life. Clinical evidence is also supported by animal models in which the vulnerability to develop a schizophrenic-like phenotype likely originates…
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Keywords:
dorsal hippocampus;
treatment;
prenatal immune;
mice exposed ... See more keywords
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Published in 2019 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2019.02.008
Abstract: Nighttime lighting is one of the great conveniences of modernization; however, there is mounting evidence that inopportune light exposure can disrupt physiological and behavioral functions. Hospital patients may be particularly vulnerable to the consequences of…
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Keywords:
night;
dim light;
light night;
night impairs ... See more keywords
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Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep40661
Abstract: Glucose tolerance was measured in (nocturnal) mice exposed to light–dark stimulus patterns simulating those that (diurnal) humans would experience while working dayshift (DSS) and 2 rotating night shift patterns (1 rotating night shift per week…
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Keywords:
shift;
tolerance;
mice exposed;
glucose tolerance ... See more keywords
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Published in 2018 at "Drug and Chemical Toxicology"
DOI: 10.1080/01480545.2017.1400043
Abstract: Abstract To investigate the effect of pectin on absorption and bio-toxicity of aluminum, pectin extract (100 mg kg−1 d−1) from banana pulp was orally administrated to aluminum exposed mice (35 mg kg−1 d−1) for 6 weeks. Our result showed that body weight…
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Keywords:
mice exposed;
mice treated;
mice;
banana pectin ... See more keywords
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Published in 2019 at "Drug and Chemical Toxicology"
DOI: 10.1080/01480545.2018.1556682
Abstract: Abstract Aflatoxin M1 (AFM1) is a 4-hydroxylated metabolite of aflatoxin B1 (AFB1). It induces various toxicological effects including immunotoxicity. In the present study, we investigated the effects of AFM1 on immune system and its modulation…
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Keywords:
mir 155;
exposed afm1;
mice exposed;
mice treated ... See more keywords
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Published in 2018 at "Carcinogenesis"
DOI: 10.1093/carcin/bgy013
Abstract: In spite of the outstanding role of tobacco smoking in human carcinogenesis, it is difficult to reproduce its effects in experimental animals. Based on the knowledge that a variety of mechanisms account for a higher…
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Keywords:
response;
cigarette smoke;
time;
mice exposed ... See more keywords
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Published in 2021 at "Journal of Radiation Research"
DOI: 10.1093/jrr/rrab012
Abstract: Abstract Metformin, a first-line oral drug for type II diabetes mellitus, not only reduces blood glucose levels, but also has many other biological effects. Recent studies have been conducted to determine the protective effect of…
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Keywords:
mice exposed;
metformin;
body irradiation;
pretreatment metformin ... See more keywords
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Published in 2022 at "Sleep"
DOI: 10.1093/sleep/zsac131
Abstract: STUDY OBJECTIVES Obstructive sleep apnea (OSA) is a chronic condition characterized by intermittent hypoxia (IH) that is implicated in an increased risk of cardiovascular disease (i.e., coronary heart disease, CHD) and associated with increased overall…
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Keywords:
reserve;
mice exposed;
flow velocity;
velocity reserve ... See more keywords
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Published in 2022 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2021-0573
Abstract: Dexamethasone is a synthetic glucocorticoid that has been associated with oxidative stress in central and peripheral tissues. p-Chloro-diphenyl diselenide (p-ClPhSe)2 is an antioxidant organoselenium compound. The present study aimed to evaluate whether Nrf2/Keap-1 signaling contributes…
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Keywords:
diphenyl diselenide;
mice exposed;
oxidative stress;
exposed dexamethasone ... See more keywords