GNASR201C Induces Pancreatic Cystic Neoplasms in Mice That Express Activated KRAS by Inhibiting YAP1 Signaling.
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DOI: 10.1053/j.gastro.2018.08.006
Abstract: BACKGROUND & AIMS Mutations at hotspots in GNAS, which encodes stimulatory G-protein, α subunits, are detected in approximately 60% of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas. We generated mice with KRAS-induced IPMNs that… read more here.
Keywords: mice express; activated kras; kras gnas; mice ... See more keywords