Effect of GPR84 deletion on obesity and diabetes development in mice fed long chain or medium chain fatty acid rich diets
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Nutrition"
DOI: 10.1007/s00394-017-1456-5
Abstract: PurposeAlthough there is good evidence showing that diets rich in medium chain fatty acids (MCFAs) have less marked obesogenic and diabetogenic effects than diets rich in long chain fatty acids (LCFAs), the role of the… read more here.
Keywords: chain; medium chain; gpr84; mice fed ... See more keywords
Astaxanthin Attenuates Nonalcoholic Steatohepatitis with Downregulation of Osteoprotegerin in Ovariectomized Mice Fed Choline-Deficient High-Fat Diet
Sign Up to like & getrecommendations! Published in 2022 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-022-07489-6
Abstract: Postmenopausal estrogen decline increases the risk of developing nonalcoholic steatohepatitis (NASH), and it might accelerate progression to cirrhosis and hepatocellular carcinoma. This study aimed to investigate a novel therapy for postmenopausal women who are diagnosed… read more here.
Keywords: deficient high; nonalcoholic steatohepatitis; high fat; choline deficient ... See more keywords
Mineralocorticoid receptor modulation by dietary sodium influences NAFLD development in mice.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of hepatology"
DOI: 10.1016/j.aohep.2021.100357
Abstract: INTRODUCTION AND OBJECTIVES Nonalcoholic-fatty-liver disease (NAFLD) is considered the hepatic manifestation of metabolic syndrome (MetS). Mineralocorticoid receptor (MR) activation is associated with increased risk of MetS but few studies have assessed the role of liver… read more here.
Keywords: sodium; mineralocorticoid receptor; expression; mice fed ... See more keywords
Atherosclerotic dyslipidemia revealed by plasma lipidomics on ApoE-/- mice fed a high-fat diet.
Sign Up to like & getrecommendations! Published in 2017 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2017.05.010
Abstract: BACKGROUND AND AIMS The pathological process of atherosclerosis is closely related to lipid accumulation at arterial wall caused by lipoproteins transporting lipids through blood. In this study, we investigate the lipid composition in the plasma… read more here.
Keywords: fat diet; fed high; high fat; mice ... See more keywords
Gut microbial metabolite TMAO contributes to renal dysfunction in a mouse model of diet-induced obesity.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.09.108
Abstract: Emerging evidence shows that obesity induces renal injury and is an independent risk factor for the development of chronic kidney disease (CKD), even without diabetes or hyperglycemia. Although multiple metabolic factors have been suggested to… read more here.
Keywords: obesity; dysfunction; tmao; contributes renal ... See more keywords
Sphingomyelin synthase 2 loss suppresses steatosis but exacerbates fibrosis in the liver of mice fed with choline-deficient, L-amino acid-defined, high-fat diet.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.09.142
Abstract: Sphingomyelin synthase 2 (SMS2) regulates sphingomyelin synthesis and contributes to obesity and hepatic steatosis. Here, we investigated the effect of SMS2 deficiency on liver fibrosis in mice fed with choline-deficient, L-amino acid-defined, high-fat diet (CDAHFD)… read more here.
Keywords: fed choline; sms2 deficiency; steatosis; sphingomyelin synthase ... See more keywords
Alterations in nociception and morphine antinociception in mice fed a high-fat diet
Sign Up to like & getrecommendations! Published in 2018 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2017.06.019
Abstract: Currently, more than 78.6 million adults in the United States are obese. A majority of the patient population receiving treatment for pain symptoms is derived from this subpopulation. Environmental factors, including the increased availability of… read more here.
Keywords: morphine; high fat; antinociception; mice ... See more keywords
DHA supplementation prevent the progression of NASH via GPR120 signaling
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2017.11.046
Abstract: ABSTRACT Nonalcoholic steatohepatitis (NASH) is one of the most common liver diseases involving chronic accumulation of fat and inflammation, often leading to advanced fibrosis, cirrhosis and carcinoma. However, the pathological mechanism for this is unknown.… read more here.
Keywords: cdahf diet; mice; gpr120; mice fed ... See more keywords
The effect of kefir produced from natural kefir grains on the intestinal microbial populations and antioxidant capacities of Balb/c mice.
Sign Up to like & getrecommendations! Published in 2019 at "Food research international"
DOI: 10.1016/j.foodres.2018.10.080
Abstract: Kefir is a probiotic and fermented dairy product authentically produced from kefir grains. Kefir grain, as a natural starter culture, contains numerous lactic acid bacteria, acetic acid bacteria and yeasts within a polysaccharide structure. True… read more here.
Keywords: kefir; kefir grains; fed kefir; kefir produced ... See more keywords
A human milk oligosaccharide, 2′-fucosyllactose, enhances the immunity in mice fed an infant formula milk diet
Sign Up to like & getrecommendations! Published in 2019 at "International Dairy Journal"
DOI: 10.1016/j.idairyj.2019.07.001
Abstract: Abstract The immune effect of 2′-fucosyllactose (2′FL) in mice fed an infant formula (IF) milk diet was studied. Forty-five BALB/C mice were randomly divided into 3 groups: control, and low and high dose of 2′FL.… read more here.
Keywords: infant formula; milk; fed infant; milk diet ... See more keywords
Tetrahydrocurcumin attenuates phase I metabolizing enzyme-triggered oxidative stress in mice fed a high-fat and high-fructose diet
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2019.02.021
Abstract: Abstract Excessive consumption of a fat- and/or fructose-rich hypercaloric diet leads to metabolic syndromes. This study aimed to investigate the hepatoprotective effects of tetrahydrocurcumin (THC), an anti-oxidant metabolite of curcumin, in a hypercaloric diet-induced oxidative… read more here.
Keywords: fed high; hffd; stress; oxidative stress ... See more keywords