Human neutrophil peptide-1 promotes alcohol-induced hepatic fibrosis and hepatocyte apoptosis
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DOI: 10.1371/journal.pone.0174913
Abstract: Background and aims Neutrophil infiltration of the liver is a typical feature of alcoholic liver injury. Human neutrophil peptide (HNP)-1 is an antimicrobial peptide secreted by neutrophils. The aim of this study was to determine… read more here.
Keywords: mice mice; apoptosis; hepatic fibrosis; hepatocyte apoptosis ... See more keywords
Intestinal edema induced by LPS-induced endotoxemia is associated with an inflammasome adaptor ASC
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DOI: 10.1371/journal.pone.0281746
Abstract: The apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC)/caspase-1/interleukin(IL)-1β axis, also known as the inflammasome pathway, is indispensable for IL-1β activation in response to various pathogens or own damages. Previously, we developed an NLRP3-inflammasome… read more here.
Keywords: edema; induced endotoxemia; lps induced; mice mice ... See more keywords