Pharmacokinetic modeling of PSMA targeted nanobubbles for quantification of extravasation and binding in mice models of prostate cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Medical physics"
DOI: 10.1002/mp.15962
Abstract: PURPOSE Contrast-enhanced ultrasound (CEUS) by injection of microbubbles (MBs) has shown promise as a cost-effective imaging modality for prostate cancer (PCa) detection. More recently, nanobubbles (NBs) have been proposed as novel ultrasound contrast agents. Unlike… read more here.
Keywords: mice models; prostate cancer; cancer; psma targeted ... See more keywords
Hepatic SIRT6 deficit promotes liver tumorigenesis in the mice models
Sign Up to like & getrecommendations! Published in 2020 at "Genes and Diseases"
DOI: 10.1016/j.gendis.2020.08.007
Abstract: Abstract Background SIRT6 belongs to class III sirtuin family with NAD+ -dependent histone deacetylase activities and controls multiple processes including aging, metabolism and inflammation. In recent years, increasing studies showed tumor suppressor role of SIRT6… read more here.
Keywords: sirt6 deficit; hepatic sirt6; mice models; promotes liver ... See more keywords
Evaluation of Nitric Oxide Fluctuation Via a Fast, Responsive Fluorescent Probe in Idiopathic Pulmonary Fibrosis Cells and Mice Models.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c05643
Abstract: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and fatal interstitial pneumonia with unknown pathogenesis. Early diagnosis and therapeutic intervention are essential for improving the prognosis of patients with IPF. The level of nitric oxide… read more here.
Keywords: probe; nitric oxide; pulmonary fibrosis; idiopathic pulmonary ... See more keywords
Evaluation of Glutathione S-Transferase Inhibition Effects on Idiopathic Pulmonary Fibrosis Therapy with a Near-Infrared Fluorescent Probe in Cell and Mice Models.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b00713
Abstract: Idiopathic pulmonary fibrosis (IPF) is a lung-limited and progressive fibrotic disease. The early diagnosis and therapies of IPF are still full of clinical challenges. Glutathione S-transferase (GSTs) plays significant roles in promoting the formation of… read more here.
Keywords: fluorescent probe; fibrosis; idiopathic pulmonary; mice models ... See more keywords
Camel Whey Protein and Baicalein Suppressed Mast Cell Degranulation in Mice Models of IgE- and Non-IgE-Mediated Anaphylaxes: Potential Mechanisms on Downstream Cell Signaling of Mast Cells
Sign Up to like & getrecommendations! Published in 2024 at "Immunological Investigations"
DOI: 10.1080/08820139.2024.2400538
Abstract: ABSTRACT Introduction Novel treatments are being researched to develop more safe and effective protective medications for anaphylaxis. Camel whey protein (CWP) and baicalein (BAC, one of the major flavones) have multiple beneficial properties including anti-inflammatory… read more here.
Keywords: camel whey; cell signaling; mice models; cell ... See more keywords
Skeletal Muscle Uncoupling Proteins in Mice Models of Obesity
Sign Up to like & getrecommendations! Published in 2022 at "Metabolites"
DOI: 10.3390/metabo12030259
Abstract: Obesity and accompanying type 2 diabetes are among major and increasing worldwide problems that occur fundamentally due to excessive energy intake during its expenditure. Endotherms continuously consume a certain amount of energy to maintain core… read more here.
Keywords: energy; uncoupling proteins; muscle; mice models ... See more keywords
99mTc-Labeled Iron Oxide Nanoparticles as Dual-Modality Contrast Agent: A Preliminary Study from Synthesis to Magnetic Resonance and Gamma-Camera Imaging in Mice Models
Sign Up to like & getrecommendations! Published in 2022 at "Nanomaterials"
DOI: 10.3390/nano12152728
Abstract: The combination of two imaging modalities in a single agent has received increasing attention during the last few years, since its synergistic action guarantees both accurate and timely diagnosis. For this reason, dual-modality contrast agents… read more here.
Keywords: dual modality; magnetic resonance; gamma camera; modality contrast ... See more keywords
Advancing Human Vaccine Development Using Humanized Mouse Models
Sign Up to like & getrecommendations! Published in 2024 at "Vaccines"
DOI: 10.3390/vaccines12091012
Abstract: The development of effective vaccines against infectious diseases remains a critical challenge in global health. Animal models play a crucial role in vaccine development by providing valuable insights into the efficacy, safety, and mechanisms of… read more here.
Keywords: human vaccine; vaccine development; mice models; human immune ... See more keywords
Appraising the neuroprotective competence of nitrogen-enriched Arthrospira platensis in comparison to commercial resource in depressed mice models
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Reports in Pharmaceutical Sciences"
DOI: 10.4103/jrptps.jrptps_54_18
Abstract: Back ground: Arthrospira platensis encompasses vital nutrients and is commercialized globally. It comprises of imperative resource that has the potential to combat neurological deformities caused due to stress and anxiety. Objective: This work evaluates the… read more here.
Keywords: depressed mice; nitrogen enriched; resource; mice models ... See more keywords