Induction of alopecia areata in C3H/HeJ mice using cryopreserved lymphocytes.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2021.04.009
Abstract: BACKGROUND Alopecia areata (AA) is an autoimmune disease resulting in non-scarring hair loss. Animal models are useful means to identify candidates for therapeutic agents. The C3H/HeJ mouse AA model induced via transferring cultured lymphoid cells… read more here.
Keywords: alopecia areata; using cryopreserved; c3h hej; cryopreserved lymphocytes ... See more keywords
Cross-site Reproducibility of Social Deficits in Group-housed BTBR Mice Using Automated Longitudinal Behavioural Monitoring
Sign Up to like & getrecommendations! Published in 2020 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2020.04.045
Abstract: Social withdrawal is associated with a variety of neuropsychiatric disorders, including neurodevelopmental disorders. Rodent studies provide the opportunity to study neurobiological mechanisms underlying social withdrawal, however, homologous paradigms to increase translatability of social behaviour between… read more here.
Keywords: cross site; reproducibility; mice; mice using ... See more keywords
Quantitative evaluation of incomplete preweaning lethality in mice by using the CRISPR/Cas9 system
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-34270-5
Abstract: Various molecular biology techniques implementing genome editing have made it possible to generate mouse mutants for nearly all known genes; as a result, the International Mouse Phenotyping Consortium (IMPC) database listing the phenotypes of genetically… read more here.
Keywords: mice using; crispr cas9; mice; preweaning lethality ... See more keywords
Modeling spontaneous opioid withdrawal in male and female outbred mice using traditional endpoints and hyperalgesia
Sign Up to like & getrecommendations! Published in 2022 at "Behavioural Pharmacology"
DOI: 10.1097/fbp.0000000000000714
Abstract: Opioid withdrawal significantly impacts drug dependence cycles as hyperalgesia associated with withdrawal is often a reason for continued drug use. Animal models of addiction are important tools for studying how drug dependence and withdrawal impact… read more here.
Keywords: using traditional; withdrawal; male female; opioid withdrawal ... See more keywords
Using c-kit to genetically target cerebellar molecular layer interneurons in adult mice
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0179347
Abstract: The cerebellar system helps modulate and fine-tune motor action. Purkinje cells (PCs) provide the sole output of the cerebellar cortex, therefore, any cerebellar involvement in motor activity must be driven by changes in PC firing… read more here.
Keywords: layer; adult mice; layer interneurons; molecular layer ... See more keywords