Jorgensen–Hayashi organocatalyst/Brønsted acid-tethered multifunctional polymeric nanospheres for complex asymmetric multicomponent/multicatalysed organocatalysis: Heterogeneous Michael/Michael/aldol organocascade and [4+2] cycloaddition reactions
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Catalysis"
DOI: 10.1016/j.mcat.2017.09.034
Abstract: Abstract Heterogeneous multicomponent/multicatalysed asymmetric organocascade reaction in green manner is a challenging task owing to mass transfer limitation and cooperative catalysis of double or multiple catalysts. In this work, a novel type of nanosphere-supported multifunctional… read more here.
Keywords: multicomponent multicatalysed; michael michael; michael; aldol organocascade ... See more keywords
Organocatalytic Enantioselective Michael-Michael-Michael-Aldol Condensation Reactions: Control of Six Stereocenters in a Quadruple-Cascade Asymmetric Synthesis of Polysubstituted Spirocyclic Oxindoles.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b02962
Abstract: An organocatalyzed enantioselective Michael-Michael-Michael-aldol cascade reaction for the construction of cyclopentane fused spirooxindoles was achieved. The domino reaction provided the spirooxindoles with six contiguous stereocenters including a quaternary center in good yields (55-64%) with excellent… read more here.
Keywords: michael michael; michael; michael aldol; enantioselective michael ... See more keywords
Heterogeneous enantioselective synthesis of chromans via the oxa-Michael-Michael cascade reaction synergically catalyzed by grafted chiral bases and inherent hydroxyls on mesoporous silica surface.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc03556j
Abstract: A heterogeneous enantioselective oxa-Michael-Michael reaction for the synthesis of chromans has been developed on a heterogeneous acid-base synergic catalyst with inherent silica as acidic sites and immobilized chiral amines as basic sites. Final products were… read more here.
Keywords: oxa michael; michael michael; michael; synthesis chromans ... See more keywords
Structural Analysis of the Michael-Michael Ring Closure (MIMIRC) Reaction Products
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27092810
Abstract: A representative number of decalin and hydrindane derivatives 2a–l were prepared in 11–91% yield by means of a cascade reaction of cyclohexanone/cyclopentanone enolates and methyl acrylate through a Michael–Michael ring closure (MIMIRC) process. The relative… read more here.
Keywords: reaction; michael ring; stereochemistry; ring closure ... See more keywords