N-Benzyloxyacrylamides as Bisnucleophiles in an Organocatalyzed Domino aza-Michael/Morita-Baylis-Hillman Sequence.
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DOI: 10.1021/acs.orglett.4c00295
Abstract: We herein describe a stereoselective organocatalyzed aza-Michael/Morita-Baylis-Hillman domino reaction between readily accessible acrylamides and α,β-unsaturated carbonyls. This novel, PPh3-promoted atom economic one-pot process features medium to good yields and good stereoselectivity leading to variously substituted… read more here.
Keywords: baylis hillman; aza michael; michael morita; morita baylis ... See more keywords