Synthesis of Unsymmetric Bis(Phosphine) Monoxides (BPMO) and NHC‐Phosphine Oxides through Michaelis‐Arbuzov Reactions of Phosphinite Esters
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DOI: 10.1002/ejoc.202500131
Abstract: A modular synthesis of bis(phosphine) monoxide (BPMO) ligands has been realized using the Michaelis‐Arbuzov reaction of dialkylphosphinite esters. The modular synthetic method allows the chemoselective synthesis of BPMO ligands in which the substituents on the… read more here.
Keywords: nhc phosphine; phosphine; synthesis unsymmetric; michaelis arbuzov ... See more keywords
Improvements, Variations and Biomedical Applications of the Michaelis–Arbuzov Reaction
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DOI: 10.3390/ijms23063395
Abstract: Compounds bearing the phosphorus–carbon (P–C) bond have important pharmacological, biochemical, and toxicological properties. Historically, the most notable reaction for the formation of the P–C bond is the Michaelis–Arbuzov reaction, first described in 1898. The classical… read more here.
Keywords: arbuzov reaction; reaction; biomedical applications; variations biomedical ... See more keywords