QIL1-dependent assembly of MICOS complex–lethal mutation in C19ORF70 resulting in liver disease and severe neurological retardation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Human Genetics"
DOI: 10.1038/s10038-018-0442-y
Abstract: Seven subunits of the mitochondrial contact site and cristae junction (CJ) organizing system (MICOS) in humans have been recently described in function and structure. QIL1 (also named MIC13) is a small complex that is crucial… read more here.
Keywords: qil1; qil1 dependent; dependent assembly; micos complex ... See more keywords
The Core MICOS Complex Subunit mic60 has Been Substituted by Two Cryptic Mitofilin-containing Proteins in Euglenozoa
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msaf289
Abstract: Cristae enclose respiratory chain complexes, making them the bioenergetic subcompartments of mitochondria. The MICOS complex is among the inducers of membrane curvature needed for crista formation. Resembling the respiratory chain complexes, MICOS is organized around… read more here.
Keywords: mitofilin; core; two cryptic; mic60 ... See more keywords