Simultaneous Determination of Five Alkaloids by HPLC-MS/MS Combined With Micro-SPE in Rat Plasma and Its Application to Pharmacokinetics After Oral Administration of Lotus Leaf Extract
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2019.01252
Abstract: An environment-friendly and efficient method for simultaneous determination of five alkaloids (nunciferine, O-nornuciferin, liriodenine, armepavine, and pronuciferine) in rat plasma was established by HPLC-MS/MS associated with micro-solid phase extraction (micro-SPE). The plasma sample was pretreated… read more here.
Keywords: rat plasma; plasma; determination; five alkaloids ... See more keywords
Micro-SPE in pipette tips as a tool for analysis of small-molecule drugs in serum.
Sign Up to like & getrecommendations! Published in 2017 at "Bioanalysis"
DOI: 10.4155/bio-2017-0033
Abstract: AIM Micro-SPE in pipette tips (μ-SPE-PT) with particle sorbent has never been used in small-molecule drug analysis. Methodology & results: μ-SPE-PT was used for the extraction of statins from biological materials followed by UHPLC-MS/MS. The… read more here.
Keywords: spe; analysis; small molecule; spe pipette ... See more keywords