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   Articles with "microarray based" as a keyword



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Evaluation of Matrix Metalloproteinase Inhibition by Peptide Microarray-Based Fluorescence Assay on Polymer Brush Substrate and in Vivo Assessment.

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recommendations! Published in 2017 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.7b15445

Abstract: Matrix metalloproteinases (MMPs) are important biomarkers and potential therapeutic targets of tumor. In this report, a peptide microarray-based fluorescence assay is developed for MMPs inhibitors evaluation through immobilization of biotin-modified peptides on the poly(glycidyl methacrylate-co-2-hydroxyethyl… read more here.

Keywords: peptide microarray; microarray; fluorescence; inhibition ... See more keywords
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Integrating microarray-based spatial transcriptomics and single-cell RNA-seq reveals tissue architecture in pancreatic ductal adenocarcinomas

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recommendations! Published in 2020 at "Nature Biotechnology"

DOI: 10.1038/s41587-019-0392-8

Abstract: Single-cell RNA sequencing (scRNA-seq) enables the systematic identification of cell populations in a tissue, but characterizing their spatial organization remains challenging. We combine a microarray-based spatial transcriptomics method that reveals spatial patterns of gene expression… read more here.

Keywords: seq; single cell; cell rna; based spatial ... See more keywords

Carbohydrate microarray-based analysis of specific interactions between saccharides from algin and influenza A viral hemagglutinin

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recommendations! Published in 2019 at "Analytical Methods"

DOI: 10.1039/c9ay01024f

Abstract: A reliable and sensitive carbohydrate microarray-based method was developed to provide a promising platform for carbohydrate-based drug discovery. read more here.

Keywords: microarray based; based analysis; carbohydrate microarray; analysis specific ... See more keywords

Highly sensitive and specific screening of EGFR mutation using a PNA microarray-based fluorometric assay based on rolling circle amplification and graphene oxide

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recommendations! Published in 2019 at "RSC Advances"

DOI: 10.1039/c9ra06758b

Abstract: A facile peptide nucleic acid microarray-based fluorometric method was developed for sensitive and specific detection of EGFR mutation by using rolling circle amplification, graphene oxide, and a fluorescently-labeled detection probe. read more here.

Keywords: egfr mutation; microarray based; rolling circle; sensitive specific ... See more keywords

Microarray-Based Nucleic Acid Assay and MALDI-TOF MS Analysis for the Detection of Gram-Negative Bacteria in Direct Blood Cultures

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recommendations! Published in 2019 at "American Journal of Clinical Pathology"

DOI: 10.1093/ajcp/aqy118

Abstract: Objectives To compare a microarray-based identification and resistance determination system (blood culture gram-negative [BC-GN]; Nanosphere, Northbrook, IL) with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) for direct blood cultures (BCs). Methods BC-GN and MALDI-TOF… read more here.

Keywords: blood cultures; maldi tof; gram negative; tof ... See more keywords

Dual-Domain Reporter Approach for Multiplex Identification of Major SARS-CoV-2 Variants of Concern in a Microarray-Based Assay

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recommendations! Published in 2023 at "Biosensors"

DOI: 10.3390/bios13020269

Abstract: Since the emergence of the COVID-19 pandemic in December 2019, the SARS-CoV-2 virus continues to evolve into many variants emerging around the world. To enable regular surveillance and timely adjustments in public health interventions, it… read more here.

Keywords: cov variants; dual domain; microarray based; domain ... See more keywords

Microarray-Based Avidity Assay for Assessment of Thyroid Autoantibodies

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recommendations! Published in 2025 at "Diagnostics"

DOI: 10.3390/diagnostics15030341

Abstract: Background/Objectives: The aim of this study was to evaluate the avidity of thyroid autoantibodies (Abs) in sera of patients with autoimmune thyroid disease (AITD) and thyroid autoantibody carriers without diagnosed AITD. Methods: A hydrogel microarray-based… read more here.

Keywords: autoantibody carriers; thyroid autoantibodies; microarray based; thyroid ... See more keywords

Diagnostic Accuracy of Methods for Detection of Antibodies against Type I Interferons in Patients with Endocrine Disorders

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recommendations! Published in 2022 at "Journal of Personalized Medicine"

DOI: 10.3390/jpm12121948

Abstract: Autoantibodies against type 1 interferons (IFN-I) are a highly specific marker for type 1 autoimmune polyglandular syndrome (APS-1). Moreover, determination of antibodies to omega-interferon (IFN-ω) and alpha2-interferon (IFN-α2) allows a short-term diagnosis in patients with… read more here.

Keywords: detection antibodies; microarray based; type interferons; endocrine disorders ... See more keywords