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Influence of media composition on recombinant monoclonal IgA1 glycosylation analysed by lectin-based protein microarray and MALDI-MS

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Published in 2020 at "Journal of Biotechnology"

DOI: 10.1016/j.jbiotec.2020.03.009

Abstract: Abstract Glycosylation of therapeutic glycoproteins significantly affects their physico-chemical properties, bioactivity and immunogenicity. The determination of glycan composition is highly important regarding their development and production. Therefore, there is a demand for analytical techniques enabling… read more here.

Keywords: protein microarray; based protein; lectin based; iga1 ... See more keywords