Design, Formulation, and Evaluation of Novel Dissolving Microarray Patches Containing Rilpivirine for Intravaginal Delivery.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201801510
Abstract: Antiretroviral (ARV) drugs have, for many years, been studied and administered in the prevention and treatment of human immunodeficiency virus (HIV). Intramuscular (IM) injection of long acting (LA) ARVs are in clinical development, but injectable… read more here.
Keywords: microarray patches; delivery; dissolving microarray; rpv ... See more keywords
Design of a Novel Delivery Efficiency Feedback System for Biphasic Dissolving Microarray Patches Based on Poly(Lactic Acid) and Moisture‐Indicating Silica
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202304082
Abstract: Dissolving microarray patches (DMAPs) represent an innovative approach to minimally invasive transdermal drug delivery, demonstrating efficacy in delivering both small and large therapeutic molecules. However, concerns raised in end‐user surveys have hindered their commercialization efforts.… read more here.
Keywords: microarray patches; delivery; feedback system; dissolving microarray ... See more keywords
Microarray patches enable the development of skin-targeted vaccines against COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Drug Delivery Reviews"
DOI: 10.1016/j.addr.2021.01.022
Abstract: The COVID-19 pandemic is a serious threat to global health and the global economy. The ongoing race to develop a safe and efficacious vaccine to prevent infection by SARS-CoV-2, the causative agent for COVID-19, highlights… read more here.
Keywords: development skin; microarray patches; skin; patches enable ... See more keywords
Development, evaluation and pharmacokinetic assessment of polymeric microarray patches for transdermal delivery of vancomycin hydrochloride.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.0c00431
Abstract: Methicillin-resistant Staphylococcus aureus (MRSA) can cause harmful and potentially deadly infections. Vancomycin remains the first-line antibiotic treatment for MRSA-derived infections. Nevertheless, as a peptide drug, it is poorly absorbed when administered orally due to its… read more here.
Keywords: transdermal delivery; microarray patches; delivery vancomycin; delivery ... See more keywords
Control of Klebsiella pneumoniae Infection in Mice by Using Dissolving Microarray Patches Containing Gentamicin
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DOI: 10.1128/aac.02612-18
Abstract: Using a murine model of Klebsiella pneumoniae bacterial infection, we demonstrate that gentamicin dissolving microarray patches, applied to murine ears, could control K. pneumoniae infection. Mice treated with microarray patches had reduced bacterial burden in… read more here.
Keywords: gentamicin; pneumoniae infection; infection; dissolving microarray ... See more keywords
Estimating the future global dose demand for measles–rubella microarray patches
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Public Health"
DOI: 10.3389/fpubh.2022.1037157
Abstract: Background Progress toward measles and rubella (MR) elimination has stagnated as countries are unable to reach the required 95% vaccine coverage. Microarray patches (MAPs) are anticipated to offer significant programmatic advantages to needle and syringe… read more here.
Keywords: microarray patches; coverage; pdr; scenario ... See more keywords
Accelerating the Development of Measles and Rubella Microarray Patches to Eliminate Measles and Rubella: Recent Progress, Remaining Challenges
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Public Health"
DOI: 10.3389/fpubh.2022.809675
Abstract: Measles and rubella microarray patches (MR-MAPs) are critical in achieving measles and rubella eradication, a goal highly unlikely to meet with current vaccines presentations. With low commercial incentive to MAP developers, limited and uncertain funding,… read more here.
Keywords: measles rubella; rubella microarray; microarray patches; progress ... See more keywords
Poly(acrylic acid)/Poly(vinyl alcohol) Microarray Patches for Continuous Transdermal Delivery of Levodopa and Carbidopa: In Vitro and In Vivo Studies
Sign Up to like & getrecommendations! Published in 2024 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics16050676
Abstract: Levodopa (LD) has been the most efficacious medication and the gold standard therapy for Parkinson’s disease (PD) for decades. However, its long-term administration is usually associated with motor complications, which are believed to be the… read more here.
Keywords: poly acrylic; acrylic acid; delivery; microarray patches ... See more keywords