Fragment Ends of Circulating Microbial DNA as Signatures for Pathogen Detection in Sepsis.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical chemistry"
DOI: 10.1093/clinchem/hvac197
Abstract: BACKGROUND Nuclear-derived cell-free DNA (cfDNA) molecules in blood plasma are nonrandomly fragmented, bearing a wealth of information related to tissues of origin. DNASE1L3 (deoxyribonuclease 1 like 3) is an important player in shaping the fragmentation… read more here.
Keywords: microbial cfdna; cfdna; microbial dna; end motif ... See more keywords
Peripheral Blood Microbiome Analysis via Noninvasive Prenatal Testing Reveals the Complexity of Circulating Microbial Cell-Free DNA
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00414-22
Abstract: While circulating cell-free DNA (cfDNA) has been becoming a powerful marker for noninvasive identification of infectious pathogens in liquid biopsy specimens, a baseline for microbial cfDNA in healthy individuals is urgently needed for the proper… read more here.
Keywords: cell free; cfdna; microbial cfdna; free dna ... See more keywords