Oral Supramolecular Adsorbent for Preventing Chemo‐Induced Gastrointestinal Mucositis and Microbial Dysbiosis and for Enhancing Chemoimmunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202205299
Abstract: The addition of immune checkpoint blockade (ICB) to cytotoxic chemotherapy has emerged as the first‐line treatment for multiple cancers. Paradoxically, cytotoxic chemotherapy may limit the therapeutic potential of ICB by significantly impairing the largest immune… read more here.
Keywords: microbial dysbiosis; mucositis microbial; spora sn9; adsorbent ... See more keywords
Acupuncture inhibits neuroinflammation and gut microbial dysbiosis in a mouse model of Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2020 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2020.08.015
Abstract: Growing evidences show that gut microbiota is associated with the pathogenesis of Parkinson's disease (PD) and the gut-brain axis can be promising target for the development of the therapeutic strategies for PD. Acupuncture has been… read more here.
Keywords: gut microbial; parkinson disease; microbial dysbiosis; acupuncture ... See more keywords
Microbial dysbiosis reflects disease resistance in diverse coral species
Sign Up to like & getrecommendations! Published in 2021 at "Communications Biology"
DOI: 10.1038/s42003-021-02163-5
Abstract: Disease outbreaks have caused significant declines of keystone coral species. While forecasting disease outbreaks based on environmental factors has progressed, we still lack a comparative understanding of susceptibility among coral species that would help predict… read more here.
Keywords: coral species; disease susceptibility; disease; microbial dysbiosis ... See more keywords
Microbial dysbiosis and polyamine metabolism as predictive markers for early detection of pancreatic cancer.
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DOI: 10.1093/carcin/bgz116
Abstract: The lack of tools for early detection of pancreatic ductal adenocarcinoma (PDAC) is directly correlated with the abysmal survival rates in patients. In addition to several potential detection tools under active investigation, we tested the… read more here.
Keywords: detection; microbial dysbiosis; early detection; dysbiosis polyamine ... See more keywords
Opioid‐induced microbial dysbiosis disrupts irinotecan (CPT‐11) metabolism and increases gastrointestinal toxicity in a murine model
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DOI: 10.1111/bph.16020
Abstract: Opioids are commonly used for the management of cancer‐associated pain and chemotherapy‐induced diarrhoea. The chemotherapeutic irinotecan (CPT‐11) causes severe gastrointestinal (GI) toxicity due to deconjugation of inactive metabolite SN‐38 glucuronide (SN‐38G) by bacterial β‐glucuronidases to… read more here.
Keywords: microbial dysbiosis; gastrointestinal toxicity; opioid induced; toxicity ... See more keywords
Microbial dysbiosis in a mouse model of atopic dermatitis mimics shifts in human microbiome and correlates with the key pro‐inflammatory cytokines IL‐4, IL‐33 and TSLP
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.17911
Abstract: Cutaneous bacterial dysbiosis is a characteristic hallmark of atopic dermatitis (AD), and it decisively influences the severity of the disease. Despite this, frequently used murine models of AD have not been characterized regarding the changes… read more here.
Keywords: atopic dermatitis; dysbiosis; microbial dysbiosis; dysbiosis mouse ... See more keywords
Faecal microbial dysbiosis in children with Wiskott‐Aldrich syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Scandinavian Journal of Immunology"
DOI: 10.1111/sji.12805
Abstract: Wiskott‐Aldrich syndrome (WAS) is an X‐linked primary immunodeficiency disease caused by a mutation in the WAS gene that encodes the WAS protein (WASp); up to 5‐10% of these patients develop inflammatory bowel disease (IBD). The… read more here.
Keywords: dysbiosis; faecal microbial; aldrich syndrome; dysbiosis children ... See more keywords
Determining Gut Microbial Dysbiosis: a Review of Applied Indexes for Assessment of Intestinal Microbiota Imbalances
Sign Up to like & getrecommendations! Published in 2021 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.00395-21
Abstract: Assessing “dysbiosis” in intestinal microbial communities is increasingly considered a routine analysis in microbiota studies, and it has added relevant information to the prediction and characterization of diseases and other adverse conditions. However, dysbiosis is… read more here.
Keywords: dysbiosis review; dysbiosis; microbiota; determining gut ... See more keywords
Stage-specific roles of microbial dysbiosis and metabolic disorders in rheumatoid arthritis
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DOI: 10.1136/ard-2022-222871
Abstract: Objective Rheumatoid arthritis (RA) is a progressive disease including four stages, where gut microbiome is associated with pathogenesis. We aimed to investigate stage-specific roles of microbial dysbiosis and metabolic disorders in RA. Methods We investigated… read more here.
Keywords: microbial dysbiosis; stage specific; specific roles; stage ... See more keywords
Gut microbial dysbiosis in rheumatoid arthritis: a systematic review protocol of case-control studies
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DOI: 10.1136/bmjopen-2021-052021
Abstract: Introduction Rheumatoid arthritis (RA) has a huge societal impact due to the high prevalence, irreversible joint damage and systemic complications. Gut microbiota plays an important role in the pathogenesis and progression of RA by regulating… read more here.
Keywords: microbial dysbiosis; control studies; dysbiosis; rheumatoid arthritis ... See more keywords
Gut microbial dysbiosis and its association with esophageal cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of applied biomedicine"
DOI: 10.32725/jab.2021.005
Abstract: Due to its aggressive nature and low survival rate, esophageal cancer is one of the deadliest cancer. While the intestinal microbiome significantly influences human health and disease. This research aimed to investigate and characterize the… read more here.
Keywords: esophageal cancer; microbial dysbiosis; cancer; gut microbial ... See more keywords