A Review of Gut Microbiota‐Derived Metabolites in Tumor Progression and Cancer Therapy
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202207366
Abstract: Gut microbiota‐derived metabolites are key hubs connecting the gut microbiome and cancer progression, primarily by remodeling the tumor microenvironment and regulating key signaling pathways in cancer cells and multiple immune cells. The use of microbial… read more here.
Keywords: microbial metabolites; gut microbiota; derived metabolites; cancer ... See more keywords
A cross talk between microbial metabolites and host immunity: Its relevance for allergic diseases
Sign Up to like & getrecommendations! Published in 2024 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12339
Abstract: Abstract Background Allergic diseases, including respiratory and food allergies, as well as allergic skin conditions have surged in prevalence in recent decades. In allergic diseases, the gut microbiome is dysbiotic, with reduced diversity of beneficial… read more here.
Keywords: cross talk; metabolites host; allergic diseases; talk microbial ... See more keywords
Secreted NF-κB suppressive microbial metabolites modulate gut inflammation.
Sign Up to like & getrecommendations! Published in 2022 at "Cell reports"
DOI: 10.1016/j.celrep.2022.110646
Abstract: Emerging evidence suggests that microbiome-host crosstalk regulates intestinal immune activity and predisposition to inflammatory bowel disease (IBD). NF-κB is a master regulator of immune function and a validated target for the treatment of IBD. Here,… read more here.
Keywords: secreted suppressive; suppressive microbial; microbial metabolites; gut inflammation ... See more keywords
The effect of deacetylation degree of konjac glucomannan on microbial metabolites and gut microbiota in vitro fermentation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2020.103796
Abstract: Abstract Deacetylation was a phenomenon widely existed during konjac glucomannan (KGM) processing, which highly effected its functional properties. Herein, influence of deacetylation degree (DD) of KGM on microbial metabolites and gut microbiota was studied in… read more here.
Keywords: microbial metabolites; konjac glucomannan; deacetylation; metabolites gut ... See more keywords
Microextraction of aromatic microbial metabolites by packed hypercrosslinked polystyrene from blood serum.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2019.112883
Abstract: The article is devoted to the application of modern sample preparation technique - microextraction by packed sorbent (MEPS) - in conjunction with non-conventional type of sorbent - hypercrosslinked polystyrene, that was investigated for the first… read more here.
Keywords: hypercrosslinked polystyrene; microbial metabolites; serum; microextraction ... See more keywords
Predicted Adsorption Affinity for Enteric Microbial Metabolites to Metal and Carbon Nanomaterials
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Chemical Information and Modeling"
DOI: 10.1021/acs.jcim.2c00492
Abstract: Ingested nanomaterials are exposed to many metabolites that are produced, modified, or regulated by members of the enteric microbiota. The adsorption of these metabolites potentially affects the identity, fate, and biodistribution of nanomaterials passing the… read more here.
Keywords: adsorption; microbial metabolites; metal carbon; affinity ... See more keywords
Erratum: Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes
Sign Up to like & getrecommendations! Published in 2017 at "Nature Immunology"
DOI: 10.1038/ni1117-1271c
Abstract: This corrects the article DOI: 10.1038/ni.3713 read more here.
Keywords: microbial metabolites; frequency autoimmune; gut microbial; erratum gut ... See more keywords
Redefining bioactive small molecules from microbial metabolites as revolutionary anticancer agents
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Gene Therapy"
DOI: 10.1038/s41417-023-00715-x
Abstract: Cancer treatment remains a significant challenge due to issues such as acquired resistance to conventional therapies and the occurrence of adverse treatment-related toxicities. In recent years, researchers have turned their attention to the microbial world… read more here.
Keywords: cancer; anticancer agents; redefining bioactive; anticancer ... See more keywords
Dereplication of microbial metabolites through database search of mass spectra
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-06082-8
Abstract: Natural products have traditionally been rich sources for drug discovery. In order to clear the road toward the discovery of unknown natural products, biologists need dereplication strategies that identify known ones. Here we report DEREPLICATOR+,… read more here.
Keywords: microbial metabolites; natural products; dereplication microbial; mass ... See more keywords
Immune recognition of microbial metabolites
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Immunology"
DOI: 10.1038/s41577-019-0252-2
Abstract: Mucosal immunology research continues its fascination with microbial metabolites. In 2019, researchers uncovered extended functions for microbial metabolites in immunity, deepening our understanding of the regulation and function of metabolite-reactive immune cells, and revealed the… read more here.
Keywords: microbial metabolites; immune recognition; recognition microbial; immune cells ... See more keywords
Gut microbial metabolites reveal diet-dependent metabolic changes induced by nicotine administration
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-51528-3
Abstract: The gut microbiota has emerged as an important factor that potentially influences various physiological functions and pathophysiological processes such as obesity and type 2 diabetes mellitus. Accumulating evidence from human and animal studies suggests that… read more here.
Keywords: microbial metabolites; gut microbial; nicotine administration; gut microbiota ... See more keywords