A Review of Gut Microbiota‐Derived Metabolites in Tumor Progression and Cancer Therapy
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202207366
Abstract: Gut microbiota‐derived metabolites are key hubs connecting the gut microbiome and cancer progression, primarily by remodeling the tumor microenvironment and regulating key signaling pathways in cancer cells and multiple immune cells. The use of microbial… read more here.
Keywords: microbial metabolites; gut microbiota; derived metabolites; cancer ... See more keywords
Secreted NF-κB suppressive microbial metabolites modulate gut inflammation.
Sign Up to like & getrecommendations! Published in 2022 at "Cell reports"
DOI: 10.1016/j.celrep.2022.110646
Abstract: Emerging evidence suggests that microbiome-host crosstalk regulates intestinal immune activity and predisposition to inflammatory bowel disease (IBD). NF-κB is a master regulator of immune function and a validated target for the treatment of IBD. Here,… read more here.
Keywords: secreted suppressive; suppressive microbial; microbial metabolites; gut inflammation ... See more keywords
The effect of deacetylation degree of konjac glucomannan on microbial metabolites and gut microbiota in vitro fermentation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2020.103796
Abstract: Abstract Deacetylation was a phenomenon widely existed during konjac glucomannan (KGM) processing, which highly effected its functional properties. Herein, influence of deacetylation degree (DD) of KGM on microbial metabolites and gut microbiota was studied in… read more here.
Keywords: microbial metabolites; konjac glucomannan; deacetylation; metabolites gut ... See more keywords
Microextraction of aromatic microbial metabolites by packed hypercrosslinked polystyrene from blood serum.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2019.112883
Abstract: The article is devoted to the application of modern sample preparation technique - microextraction by packed sorbent (MEPS) - in conjunction with non-conventional type of sorbent - hypercrosslinked polystyrene, that was investigated for the first… read more here.
Keywords: hypercrosslinked polystyrene; microbial metabolites; serum; microextraction ... See more keywords
Predicted Adsorption Affinity for Enteric Microbial Metabolites to Metal and Carbon Nanomaterials
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Chemical Information and Modeling"
DOI: 10.1021/acs.jcim.2c00492
Abstract: Ingested nanomaterials are exposed to many metabolites that are produced, modified, or regulated by members of the enteric microbiota. The adsorption of these metabolites potentially affects the identity, fate, and biodistribution of nanomaterials passing the… read more here.
Keywords: adsorption; microbial metabolites; metal carbon; affinity ... See more keywords
Erratum: Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes
Sign Up to like & getrecommendations! Published in 2017 at "Nature Immunology"
DOI: 10.1038/ni1117-1271c
Abstract: This corrects the article DOI: 10.1038/ni.3713 read more here.
Keywords: microbial metabolites; frequency autoimmune; gut microbial; erratum gut ... See more keywords
Dereplication of microbial metabolites through database search of mass spectra
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-06082-8
Abstract: Natural products have traditionally been rich sources for drug discovery. In order to clear the road toward the discovery of unknown natural products, biologists need dereplication strategies that identify known ones. Here we report DEREPLICATOR+,… read more here.
Keywords: microbial metabolites; natural products; dereplication microbial; mass ... See more keywords
Immune recognition of microbial metabolites
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Immunology"
DOI: 10.1038/s41577-019-0252-2
Abstract: Mucosal immunology research continues its fascination with microbial metabolites. In 2019, researchers uncovered extended functions for microbial metabolites in immunity, deepening our understanding of the regulation and function of metabolite-reactive immune cells, and revealed the… read more here.
Keywords: microbial metabolites; immune recognition; recognition microbial; immune cells ... See more keywords
The role of key gut microbial metabolites in the development and treatment of cancer
Sign Up to like & getrecommendations! Published in 2022 at "Gut Microbes"
DOI: 10.1080/19490976.2022.2038865
Abstract: ABSTRACT In recent years, the role of gut microbial metabolites on the inhibition and progression of cancer has gained significant interest in anticancer research. It has been established that the gut microbiome plays a pivotal… read more here.
Keywords: microbial metabolites; role; development treatment; gut microbial ... See more keywords
Microbial metabolites in colorectal tumorigenesis and cancer therapy
Sign Up to like & getrecommendations! Published in 2023 at "Gut Microbes"
DOI: 10.1080/19490976.2023.2203968
Abstract: ABSTRACT Trillions of microbes are indigenous to the human gastrointestinal tract, together forming an ecological community known as the gut microbiota. The gut microbiota is involved in dietary digestion to produce various metabolites. In healthy… read more here.
Keywords: tumorigenesis cancer; colorectal tumorigenesis; microbial metabolites; metabolites colorectal ... See more keywords
Microbial Metabolites as Ligands to Xenobiotic Receptors: Chemical Mimicry as Potential Drugs of the Future
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DOI: 10.1124/dmd.122.000860
Abstract: Xenobiotic receptors, such as the pregnane X receptor, regulate multiple host physiologic pathways including xenobiotic metabolism, certain aspects of cellular metabolism, and innate immunity. These ligand-dependent nuclear factors regulate gene expression via genomic recognition of… read more here.
Keywords: drugs future; metabolism; metabolites ligands; microbial metabolites ... See more keywords