Designing Anti-Microbial Peptides Against Major β-Lactamase Enzymes in Clinically Important Gram-Negative Bacterial Pathogens: An In-Silico Study
Sign Up to like & getrecommendations! Published in 2022 at "Probiotics and Antimicrobial Proteins"
DOI: 10.1007/s12602-022-09929-1
Abstract: Anti-microbial resistance (AMR) creating healthcare concerns worldwide requires ardent exploration of therapeutic alternatives. Although anti-microbial peptides (AMP) are popular for broad-spectrum activity, recent evidence of increasing resistance to membrane-acting AMPs by ESKAPE pathogens has compelled… read more here.
Keywords: study; anti microbial; microbial peptides; designing anti ... See more keywords
Exploring the Microbial Peptides Derived from the Human Gut Microbiota to Regulate Class B GPCRS Using an In Silico Approach
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DOI: 10.1021/acsomega.5c03268
Abstract: Class B G-protein coupled receptors (GPCRs) are significant therapeutic recipients in cardiovascular, neurological, and metabolic diseases. The human gut microbiome is a complex microbial ecology recently identified as a possible source of bioactive peptides that… read more here.
Keywords: microbial peptides; human gut; class; peptides derived ... See more keywords
Plasma from patients with anti-glomerular basement membrane disease could recognize microbial peptides
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DOI: 10.1371/journal.pone.0174553
Abstract: Infection has long been suspected as a trigger of autoimmune diseases, and molecular mimicry mechanism was hypothesized in this study. Microbe originated peptides were searched from the Uniprot database based on a previous defined critical… read more here.
Keywords: igg igm; anti gbm; disease; plasma patients ... See more keywords