Articles with "microbial translocation" as a keyword



The role of TSPO PET in assessing neuroinflammation

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Published in 2017 at "Journal of Neurology"

DOI: 10.1007/s00415-017-8565-1

Abstract: Despite the advent of combined antiretroviral therapy and the consequent effective control of HIV RNA in both the serum and CSF, many HIV-positive patients still develop HIV-associated brain disease, including cognitive impairment. It has been… read more here.

Keywords: pet; role tspo; hiv patients; hiv ... See more keywords

Helminth driven gut inflammation and microbial translocation associate with altered vaccine responses in rural Uganda

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Published in 2025 at "NPJ Vaccines"

DOI: 10.1038/s41541-025-01116-x

Abstract: Vaccine responses are sometimes impaired in rural, low-income settings. Helminth-associated gut barrier dysfunction and microbial translocation (MT) may be implicated. We used samples from a trial of praziquantel treatment-effects on vaccine responses in Schistosoma mansoni… read more here.

Keywords: gut inflammation; fob; vaccine responses; microbial translocation ... See more keywords

Intestinal Barrier Dysfunction and Microbial Translocation in Human Immunodeficiency Virus–Infected Pregnant Women Are Associated With Preterm Birth

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Published in 2018 at "Clinical Infectious Diseases"

DOI: 10.1093/cid/ciy253

Abstract: Background Preterm birth (PTB) rates are high in human immunodeficiency virus (HIV)-infected populations, even when on treatment. Still, only a subset of all births in HIV-infected pregnant women result in PTB, suggesting that risk factors… read more here.

Keywords: barrier; pregnant women; microbial translocation; infected pregnant ... See more keywords
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Gut epithelial impairment, microbial translocation and immune system activation in inflammatory bowel disease-associated spondyloarthritis.

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Published in 2020 at "Rheumatology"

DOI: 10.1093/rheumatology/keaa164

Abstract: OBJECTIVES Gut microbiota has been widely reported to be involved in systemic inflammation through microbial translocation and T cell activation in several diseases. In this work we aimed to investigate bacterial infiltration and epithelial impairment… read more here.

Keywords: microbial translocation; immune system; translocation; system activation ... See more keywords

Immune Activation and Microbial Translocation Markers in HIV-Exposed Uninfected Malawian Infants in the First Year of Life.

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Published in 2019 at "Journal of tropical pediatrics"

DOI: 10.1093/tropej/fmz022

Abstract: BACKGROUND HIV-exposed uninfected (HEU) infants show a high rate of morbidity. We aimed to investigate on biomarkers of immune activation/microbial translocation in HEU infants, evaluating the impact that infections/malnutrition can have on biomarker levels during… read more here.

Keywords: activation microbial; immune activation; first year; exposed uninfected ... See more keywords

Biomarkers of microbial translocation and generalized inflammation are associated with frailty among people with HIV

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Published in 2024 at "AIDS"

DOI: 10.1097/qad.0000000000004047

Abstract: Background: Frailty occurs at higher rates and younger ages among people with HIV (PWH) compared with the general population and is often attributed to chronic inflammation and subsequent immune exhaustion. We assessed how inflammatory biomarkers… read more here.

Keywords: people hiv; microbial translocation; inflammation; frailty ... See more keywords

Microbial translocation is associated with advanced liver fibrosis among people with HIV

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Published in 2022 at "HIV Medicine"

DOI: 10.1111/hiv.13279

Abstract: The prevalence of liver complications is increasing among people living with HIV, and microbial translocation (MT) might play a vital role. We conducted a prospective cohort study to evaluate the association between plasma biomarkers of… read more here.

Keywords: liver fibrosis; microbial translocation; among people; fibrosis among ... See more keywords

Microbial translocation into amniotic fluid of vervet monkeys is common and unrelated to adverse infant outcomes

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Published in 2019 at "Journal of Medical Primatology"

DOI: 10.1111/jmp.12432

Abstract: Amniotic fluid was collected from pregnant female African green monkeys (n = 20). Analyses indicate microbial translocation into amniotic fluid during pregnancy is typical, and microbial load reduces across gestation. Microbial translocation does not relate… read more here.

Keywords: translocation amniotic; infant; amniotic fluid; microbial translocation ... See more keywords

Anthocyanin-Rich Blackcurrant Extract Preserves Gastrointestinal Barrier Permeability and Reduces Enterocyte Damage but Has No Effect on Microbial Translocation and Inflammation After Exertional Heat Stress.

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Published in 2022 at "International journal of sport nutrition and exercise metabolism"

DOI: 10.1123/ijsnem.2021-0330

Abstract: This study investigated the effects of 7 days of 600 mg/day anthocyanin-rich blackcurrant extract intake on small intestinal permeability, enterocyte damage, microbial translocation, and inflammation following exertional heat stress. Twelve recreationally active men (maximal aerobic capacity =… read more here.

Keywords: blackcurrant extract; microbial translocation; enterocyte damage; permeability ... See more keywords

FRI0148 A study of microbial translocation in an animal model of spondyloarthritis

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Published in 2018 at "Annals of the Rheumatic Diseases"

DOI: 10.1136/annrheumdis-2018-eular.7487

Abstract: Background The intestinal microbiota is believed to have a central role in SpA pathogenesis. However, the mechanism through which enteric microbes contribute to peripheral inflammation remains enigmatic. Objectives The primary objective of this study was… read more here.

Keywords: hla b27; disease; microbial translocation; tissue ... See more keywords

Camu Camu effects on microbial translocation and systemic immune activation in ART-treated people living with HIV: protocol of the single-arm non-randomised Camu Camu prebiotic pilot study (CIHR/CTN PT032)

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Published in 2022 at "BMJ Open"

DOI: 10.1136/bmjopen-2021-053081

Abstract: Introduction Despite the success of antiretroviral therapy (ART) in transforming HIV disease into a chronic infection, people living with HIV (PLWH) remain at risk for various non-AIDS inflammatory comorbidities. Risk of non-AIDS comorbidities is associated… read more here.

Keywords: camu camu; hiv; camu; microbial translocation ... See more keywords