Acceptability of and Adherence to an Antiretroviral-Based Vaginal Microbicide among Pregnant Women in the United States
Sign Up to like & getrecommendations! Published in 2017 at "AIDS and Behavior"
DOI: 10.1007/s10461-017-1811-9
Abstract: The MTN-008 trial was the first multi-dose study conducted to evaluate the safety of a microbicide gel (2:1 randomized to tenofovir 1% or hydroxycellulose (HEC) placebo gel) during pregnancy. The study aim was to evaluate… read more here.
Keywords: antiretroviral based; pregnancy; acceptability; microbicide ... See more keywords
Safety and efficacy of G2-S16 dendrimer as microbicide in healthy human vaginal tissue explants
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-022-01350-8
Abstract: Background The absence of an effective treatment and vaccine in HIV-1 pandemic place preventive strategies such as safety and effective microbicide development as a central therapeutic approach to control HIV-1 pandemic nowadays. Results Studies of… read more here.
Keywords: microbicide; vaginal tissue; s16 dendrimer; tissue explants ... See more keywords
Evaluation of the fusion inhibitor P3 peptide as a potential microbicide to prevent HIV transmission in women
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0195744
Abstract: Microbicides are an important strategy for preventing the sexual transmission of HIV but, so far, the most advanced tenofovir-based microbicides have had modest efficacy. This has been related to adherence problems and high prevalence of… read more here.
Keywords: transmission; microbicide; hiv; activity ... See more keywords