Suhuai suckling piglet hindgut microbiome-metabolome responses to different dietary copper levels
Sign Up to like & getrecommendations! Published in 2018 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-018-9533-0
Abstract: Unabsorbed copper accumulates in the hindgut of pigs that consume high levels of dietary copper, which enhances the coselection of antibiotic-resistant bacteria and is considered detrimental to the environment and to porcine health. In our… read more here.
Keywords: metabolome responses; metabolism; copper; copper levels ... See more keywords
Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-19701-0
Abstract: Chronic obstructive pulmonary disease (COPD) is the third commonest cause of death globally, and manifests as a progressive inflammatory lung disease with no curative treatment. The lung microbiome contributes to COPD progression, but the function… read more here.
Keywords: chronic obstructive; obstructive pulmonary; disease; gut microbiome ... See more keywords
Morphine induces changes in the gut microbiome and metabolome in a morphine dependence model
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-21915-8
Abstract: Opioid analgesics are frequently prescribed in the United States and worldwide. However, serious comorbidities, such as dependence, tolerance, immunosuppression and gastrointestinal disorders limit their long-term use. In the current study, a morphine-murine model was used… read more here.
Keywords: microbiome metabolome; morphine; opioid use; gut microbiome ... See more keywords
Microbiome-metabolome signatures in mice genetically prone to develop dementia, fed a normal or fatty diet
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-23261-1
Abstract: Cognitive decline, obesity and gut dysfunction or microbial dysbiosis occur in association. Our aim was to identify gut microbiota-metabolomics signatures preceding dementia in genetically prone (3xtg) mice, with and without superimposed high-fat diet. We examined… read more here.
Keywords: fat diet; genetically prone; high fat; 3xtg mice ... See more keywords
Integrative analysis of the microbiome and metabolome in understanding the causes of sugarcane bitterness
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-85433-w
Abstract: Plant–microbe interactions can modulate the plant metabolome, but there is no information about how different soil microbiomes could affect the sugarcane metabolome and its quality. Here, we collected soil and stalk samples from bitter sugarcane… read more here.
Keywords: integrative analysis; plant; analysis; soil ... See more keywords
Changes in the gut microbiome and metabolome in a rat model of pulmonary arterial hypertension.
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1952365
Abstract: The gut microbiota is widely considered to be involved in several diseases, including atherosclerosis, obesity, chronic obstructive pulmonary disease (COPD) and pulmonary arterial hypertension (PAH). This study aimed to determine if changes in the gut… read more here.
Keywords: arterial hypertension; pulmonary arterial; gut microbiome; rat model ... See more keywords
Gastrointestinal Surgery for Inflammatory Bowel Disease Persistently Lowers Microbiome and Metabolome Diversity
Sign Up to like & getrecommendations! Published in 2020 at "Inflammatory Bowel Diseases"
DOI: 10.1093/ibd/izaa262
Abstract: Abstract Background Many studies have investigated the role of the microbiome in inflammatory bowel disease (IBD), but few have focused on surgery specifically or its consequences on the metabolome that may differ by surgery type… read more here.
Keywords: surgery; diversity; inflammatory bowel; disease ... See more keywords
Microbiome and metabolome in inflammatory bowel disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.16043
Abstract: Inflammatory bowel disease (IBD) is a chronic gastrointestinal disease of unknown etiology, involving complex interactions between the gut microbiome and host immune response. The microbial dysbiosis is well documented in IBD and significantly influences the… read more here.
Keywords: ibd; disease; inflammatory bowel; microbiome metabolome ... See more keywords
Effects of metronidazole on the fecal microbiome and metabolome in healthy dogs
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Veterinary Internal Medicine"
DOI: 10.1111/jvim.15871
Abstract: Abstract Background Metronidazole has a substantial impact on the gut microbiome. However, the recovery of the microbiome after discontinuation of administration, and the metabolic consequences of such alterations have not been investigated to date. Objectives… read more here.
Keywords: metabolome healthy; microbiome; fecal microbiome; healthy dogs ... See more keywords
Microbiome and metabolome reveal the metabolic and microbial variations induced by depression and constipation
Sign Up to like & getrecommendations! Published in 2023 at "Psychogeriatrics"
DOI: 10.1111/psyg.12934
Abstract: Depressed patients are often accompanied with constipation symptoms, and vice versa. However, the underlying mechanisms of such a bidirectional correlation have remained elusive. We aim to reveal the possible correlations between depression and constipation from… read more here.
Keywords: depression constipation; metabolome reveal; constipation; microbiome metabolome ... See more keywords
Longitudinal Analysis of the Microbiome and Metabolome in the 5xfAD Mouse Model of Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.01794-22
Abstract: Microorganisms residing within the gastrointestinal tract are implicated in the onset and progression of Alzheimer’s disease (AD) through the mediation of inflammation, exchange of small-molecules across the blood-brain barrier, and stimulation of the vagus nerve.… read more here.
Keywords: microbiome metabolome; alzheimer disease; mouse model; model ... See more keywords