Diversity and bias in oral microbiome research: A commentary
Sign Up to like & getrecommendations! Published in 2021 at "EClinicalMedicine"
DOI: 10.1016/j.eclinm.2021.100923
Abstract: The oral cavity has the second largest and most diverse microbiota of the human body, harbouring over 700 microbial species [1]. Oral microbial communities are dominated by bacteria, but also contain archaea, viruses, and eukaryotes,… read more here.
Keywords: oral microbiome; research; microbiome research; microbiome studies ... See more keywords
Are microbiome studies ready for hypothesis-driven research?
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in microbiology"
DOI: 10.1016/j.mib.2018.07.002
Abstract: Hypothesis-driven research has led to many scientific advances, but hypotheses cannot be tested in isolation: rather, they require a framework of aggregated scientific knowledge to allow questions to be posed meaningfully. This framework is largely… read more here.
Keywords: driven research; hypothesis driven; microbiome studies; studies ready ... See more keywords
Perspective and Guidelines for Metaproteomics in Microbiome Studies.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.9b00054
Abstract: The microbiome is emerging as a prominent factor affecting human health, and its dysbiosis is associated with various diseases. Compositional profiling of microbiome is increasingly being supplemented with functional characterization. Metaproteomics is intrinsically focused on… read more here.
Keywords: metaproteomics microbiome; guidelines metaproteomics; microbiome studies; perspective guidelines ... See more keywords
Reporting guidelines for human microbiome research: the STORMS checklist.
Sign Up to like & getrecommendations! Published in 2021 at "Nature medicine"
DOI: 10.1038/s41591-021-01552-x
Abstract: The particularly interdisciplinary nature of human microbiome research makes the organization and reporting of results spanning epidemiology, biology, bioinformatics, translational medicine and statistics a challenge. Commonly used reporting guidelines for observational or genetic epidemiology studies… read more here.
Keywords: medicine; microbiome research; human microbiome; epidemiology ... See more keywords
Zebrafish microbiome studies make waves
Sign Up to like & getrecommendations! Published in 2020 at "Lab Animal"
DOI: 10.1038/s41684-020-0573-6
Abstract: Zebrafish have a 50-year history as a model organism for studying vertebrate developmental biology and more recently have emerged as a powerful model system for studying vertebrate microbiome assembly, dynamics and function. In this Review,… read more here.
Keywords: studies make; microbiome; make waves; model ... See more keywords
Recruitment and Retention of Pregnant and Breastfeeding Mothers for Longitudinal Clinical Microbiome Studies (OR30-08-19).
Sign Up to like & getrecommendations! Published in 2019 at "Current developments in nutrition"
DOI: 10.1093/cdn/nzz048.or30-08-19
Abstract: Objectives Accumulating data suggest the health benefits of breastfeeding are, in part, mediated through interactions with the human microbiome. Despite these observations, recruitment of pregnant mothers in longitudinal clinical microbiome studies remains a significant challenge.… read more here.
Keywords: mothers longitudinal; microbiome studies; pregnant breastfeeding; clinical microbiome ... See more keywords
Considerations and best practices in animal science 16S ribosomal RNA gene sequencing microbiome studies
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Animal Science"
DOI: 10.1093/jas/skab346
Abstract: Abstract Microbiome studies in animal science using 16S rRNA gene sequencing have become increasingly common in recent years as sequencing costs continue to fall and bioinformatic tools become more powerful and user-friendly. The combination of… read more here.
Keywords: science; microbiome studies; 16s rrna; animal science ... See more keywords
Integrating phylogenetic and functional data in microbiome studies
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1101/2022.02.21.480893
Abstract: Microbiome functional data are frequently analyzed to identify associations between microbial gene families and sample groups of interest. This is most often performed with approaches focused on the metagenome-wide relative abundance of microbial functions. Although… read more here.
Keywords: microbiome studies; data microbiome; abundance; functional data ... See more keywords
mSphere of Influence: Translating Gut Microbiome Studies To Benefit Human Health
Sign Up to like & getrecommendations! Published in 2020 at "mSphere"
DOI: 10.1128/msphere.00592-20
Abstract: Anna M. Seekatz works in the field of the gut microbiome as it related to infectious diseases. In this “mSphere of Influence” article, she reflects on how two studies, “The impact of a consortium of… read more here.
Keywords: gut microbiome; msphere influence; influence translating; microbiome studies ... See more keywords
Data Analysis Strategies for Microbiome Studies in Human Populations—a Systematic Review of Current Practice
Sign Up to like & getrecommendations! Published in 2021 at "mSystems"
DOI: 10.1128/msystems.01154-20
Abstract: The human microbiome has emerged as an important factor in the development of health and disease. Growing interest in this topic has led to an increasing number of studies investigating the human microbiome using high-throughput… read more here.
Keywords: analysis strategies; human microbiome; microbiome studies; research ... See more keywords
A Zero-Inflated Latent Dirichlet Allocation Model for Microbiome Studies
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2020.602594
Abstract: The human microbiome consists of a community of microbes in varying abundances and is shown to be associated with many diseases. An important first step in many microbiome studies is to identify possible distinct microbial… read more here.
Keywords: latent dirichlet; model; dirichlet allocation; allocation model ... See more keywords