Articles with "microbiota" as a keyword



Association of Intratumoral Microbiota With Prognosis in Patients With Nasopharyngeal Carcinoma From 2 Hospitals in China

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Published in 2022 at "JAMA Oncology"

DOI: 10.1001/jamaoncol.2022.2810

Abstract: Key Points Question Is there characteristic microbiota in nasopharyngeal carcinoma (NPC) tissues and, if so, is it associated with prognosis? Findings In this multicenter cohort study including 802 patients with NPC, we confirmed the existence… read more here.

Keywords: nasopharyngeal carcinoma; prognosis; microbiota; intratumoral microbiota ... See more keywords

Sweat‐Permeable, Microbiota‐Preserving, Mechanically Antibacterial Patch for Long‐Term Interfacing with Perspiring Skin

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Published in 2024 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202416129

Abstract: The prolonged health monitoring using wearable technology faces challenges stemming from perspiration, including bacterial proliferation, compromised adhesion, signal quality deterioration, and user discomfort. Notably, excessive sweat fosters bacterial colonization, escalating infection risks, and compromising biomarker… read more here.

Keywords: perspiring skin; patch; long term; sweat ... See more keywords

Oral Targeted MXenzyme – Armed Probiotic Regulates Intestinal Redox and Microbiota Homeostasis to Synergistically Ameliorate Ulcerative Colitis

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Published in 2025 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202421680

Abstract: Ulcerative colitis (UC) leads to complex alterations in the intestinal microenvironment, with gut microbiota dysbiosis and excessive reactive oxygen species (ROS) being major drivers. Previously, microecological preparations have been used to restore intestinal homeostasis and… read more here.

Keywords: akk v2c; homeostasis; ulcerative colitis; microbiota homeostasis ... See more keywords

A Living Microecological Hydrogel with Microbiota Remodeling and Immune Reinstatement for Diabetic Wound Healing

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Published in 2024 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202400856

Abstract: Dysregulated skin microbiota and compromised immune responses are the major etiological factors for non‐healing diabetic wounds. Current antibacterial strategies fail to orchestrate immune responses and indiscriminately eradicate bacteria at the wound site, exacerbating the imbalance… read more here.

Keywords: living microecological; wound healing; fos gel; microecological hydrogel ... See more keywords

Extracellular Vesicles from Nanomedicine‐Trained Intestinal Microbiota Substitute for Fecal Microbiota Transplant in Treating Ulcerative Colitis

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Published in 2024 at "Advanced Materials"

DOI: 10.1002/adma.202409138

Abstract: The biosafety concerns associated with fecal microbiota transplant (FMT) limit their clinical application in treating ulcerative colitis (UC). Gut microbiota secrete abundant extracellular vesicles (Gm‐EVs), which play a critical role in bacteria‐to‐bacteria and bacteria‐to‐host communications.… read more here.

Keywords: microbiota transplant; healthy mice; intestinal microbiota; fecal microbiota ... See more keywords

Microbiota in Tumors: From Understanding to Application

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Published in 2022 at "Advanced Science"

DOI: 10.1002/advs.202200470

Abstract: Microbes with complex functions have been found to be a potential component in tumor microenvironments. Due to their low biomass and other obstacles, intratumor microbiota is poorly understood. Mucosal sites and normal adjacent tissues are… read more here.

Keywords: microbiota; understanding application; tumors understanding; intratumor microbiota ... See more keywords

Dynamic Alterations in the Respiratory Tract Microbiota of Patients with COVID‐19 and its Association with Microbiota in the Gut

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Published in 2022 at "Advanced Science"

DOI: 10.1002/advs.202200956

Abstract: Abstract The role of respiratory tract microbes and the relationship between respiratory tract and gut microbiomes in coronavirus disease 2019 (COVID‐19) remain uncertain. Here, the metagenomes of sputum and fecal samples from 66 patients with… read more here.

Keywords: microbiota; tract gut; respiratory tract;

ASPS Exhibits Anti‐Rheumatic Effects by Reprogramming Gut Microbiota and Increasing Serum γ‐Glutamylcysteine Level

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Published in 2022 at "Advanced Science"

DOI: 10.1002/advs.202205645

Abstract: Rheumatoid arthritis (RA) is an essential cause of labor loss and disability for people worldwide. Acanthopanax senticosus polysaccharide (ASPS) is one of the most important active components from A. senticosus, which exhibits various pharmacological activities… read more here.

Keywords: asps; exhibits anti; microbiota; gut microbiota ... See more keywords

Nicotinamide Mononucleotide Ameliorates Sleep Deprivation‐Induced Gut Microbiota Dysbiosis and Restores Colonization Resistance against Intestinal Infections

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Published in 2023 at "Advanced Science"

DOI: 10.1002/advs.202207170

Abstract: Gut microbiota‐mediated colonization resistance (CR) is crucial in protecting the host from intestinal infections. Sleep deprivation (SD) is an important contributor in the disturbances of intestinal homeostasis. However, whether and how SD affects host CR… read more here.

Keywords: colonization resistance; nicotinamide mononucleotide; microbiota; gut microbiota ... See more keywords

Nano‐Armed Limosilactobacillus reuteri for Enhanced Photo‐Immunotherapy and Microbiota Tryptophan Metabolism against Colorectal Cancer

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Published in 2024 at "Advanced Science"

DOI: 10.1002/advs.202410011

Abstract: Despite being a groundbreaking approach to treating colorectal cancer (CRC), the efficacy of immunotherapy is significantly compromised by the immunosuppressive tumor microenvironment and dysbiotic intestinal microbiota. Here, leveraging the superior carrying capacity and innate immunity‐stimulating… read more here.

Keywords: colorectal cancer; photo immunotherapy; limosilactobacillus reuteri; microbiota ... See more keywords

Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population

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Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202411086

Abstract: Gut microbiota is essential for the function of peripherally‐induced regulatory T (pTreg) cells. However, how commensal bacteria affect thymically derived fat‐resident Treg cells that harbor a unique expression of peroxisome proliferator‐activated receptor (PPAR)‐γ and suppress… read more here.

Keywords: ppar; gut microbiota; population; butyrate ... See more keywords