Gut Microbiota Colonization in Early Life Influences Susceptibility to Adulthood Hepatic Lipid Accumulation in High‐Fat‐Diet‐Fed Mice
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202412827
Abstract: The global prevalence of Metabolic Dysfunction‐Associated Fatty Liver Disease (MAFLD) has a rising trend. The Developmental Origins of Health and Disease (DOHaD) theory assumes that MAFLD develops throughout the entire lifecycle but it originates in… read more here.
Keywords: microbiota colonization; gut microbiota; hepatic lipid; early life ... See more keywords
Caloric restriction disrupts the microbiota and colonization resistance.
Sign Up to like & getrecommendations! Published in 2021 at "Nature"
DOI: 10.1038/s41586-021-03663-4
Abstract: Diet is a major factor that shapes the gut microbiome1, but the consequences of diet-induced changes in the microbiome for host pathophysiology remain poorly understood. We conducted a randomized human intervention study using a very-low-calorie… read more here.
Keywords: restriction; restriction disrupts; colonization resistance; caloric restriction ... See more keywords