Enhancing mucosal immunity by transient microbiota depletion
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-18248-4
Abstract: Tissue resident memory CD8+ T cells (Trm) are poised for immediate reactivation at sites of pathogen entry and provide optimal protection of mucosal surfaces. The intestinal tract represents a portal of entry for many infectious agents;… read more here.
Keywords: transient microbiota; microbiota depletion; microbiota; mucosal ... See more keywords
Antibiotic-Associated Apoptotic Enterocolitis in the Absence of a Defined Pathogen: The Role of Intestinal Microbiota Depletion*
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DOI: 10.1097/ccm.0000000000002310
Abstract: Objective: Antibiotic therapy is a major risk factor for the development of diarrhea and colitis with varying severity. Often the origin of antibiotic-associated gastrointestinal deterioration remains elusive and no specific infectious agents could be discerned.… read more here.
Keywords: microbiota depletion; antibiotic associated; microbiota; apoptotic enterocolitis ... See more keywords
Ventilator-induced lung injury is aggravated by antibiotic mediated microbiota depletion in mice
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DOI: 10.1186/s13054-018-2213-8
Abstract: BackgroundAntibiotic exposure alters the microbiota, which can impact the inflammatory immune responses. Critically ill patients frequently receive antibiotic treatment and are often subjected to mechanical ventilation, which may induce local and systemic inflammatory responses and… read more here.
Keywords: ventilator induced; ventilation; induced lung; microbiota depletion ... See more keywords