Epithelial chemerin–CMKLR1 signaling restricts microbiota-driven colonic neutrophilia and tumorigenesis by up-regulating lactoperoxidase
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DOI: 10.1073/pnas.2205574119
Abstract: Significance Epithelial antimicrobial defense is an important innate mechanism to maintain intestinal homeostasis and closely involved in the pathogenesis of inflammatory bowel disease (IBD). Chemerin, which is abundantly expressed in barrier tissues, regulates tissue inflammation… read more here.
Keywords: chemerin cmklr1; chemerin; cmklr1 signaling; microbiota driven ... See more keywords