Murine fecal microbiota transfer models selectively colonize human microbes and reveal transcriptional programs associated with response to neoadjuvant checkpoint inhibitors
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-022-03169-6
Abstract: Human gut microbial species found to associate with clinical responses to immune checkpoint inhibitors (ICIs) are often tested in mice using fecal microbiota transfer (FMT), wherein tumor responses in recipient mice may recapitulate human responses… read more here.
Keywords: microbiota transfer; fecal microbiota; microbiota; checkpoint inhibitors ... See more keywords
Long-term benefit of Microbiota Transfer Therapy on autism symptoms and gut microbiota
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-42183-0
Abstract: Many studies have reported abnormal gut microbiota in individuals with Autism Spectrum Disorders (ASD), suggesting a link between gut microbiome and autism-like behaviors. Modifying the gut microbiome is a potential route to improve gastrointestinal (GI)… read more here.
Keywords: transfer therapy; microbiota; autism; gut microbiota ... See more keywords
The impact of technical and clinical factors on fecal microbiota transfer outcomes for the treatment of recurrent Clostridioides difficile infections in Germany
Sign Up to like & getrecommendations! Published in 2019 at "United European Gastroenterology Journal"
DOI: 10.1177/2050640619839918
Abstract: Introduction Fecal microbiota transfer (FMT) is highly effective in the treatment and prevention of recurrent Clostridioides difficile infection (rCDI) with cure rates of about 80% after a single treatment. Nevertheless, the reasons for failure in… read more here.
Keywords: microbiota; recurrent clostridioides; treatment; clostridioides difficile ... See more keywords
Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study
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DOI: 10.1186/s40168-016-0225-7
Abstract: BackgroundAutism spectrum disorders (ASD) are complex neurobiological disorders that impair social interactions and communication and lead to restricted, repetitive, and stereotyped patterns of behavior, interests, and activities. The causes of these disorders remain poorly understood,… read more here.
Keywords: transfer therapy; microbiota; treatment; open label ... See more keywords
Efficacy and safety of microbiota transfer therapy for the management of autism spectrum disorder in children: a systematic review
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DOI: 10.12688/f1000research.21525.1
Abstract: Background: Autism spectrum disorder (ASD) is a neurodevelopmental condition associated with an unclear etiologic mechanism. Following suggestions in the literature of a close relation between the gut microbiota and the central nervous system development, neuroimmune… read more here.
Keywords: transfer therapy; microbiota transfer; safety microbiota;
Comparative Evaluation of Microbiota Engraftment Following Fecal Microbiota Transfer in Mice Models: Age, Kinetic and Microbial Status Matter
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.03289
Abstract: The intestinal microbiota and its functions are intricately interwoven with host physiology. Colonizing rodents with donor microbiota provides insights into host-microbiota interactions characterization and the understanding of disease physiopathology. However, a better assessment of inoculation… read more here.
Keywords: microbiota; donor microbiota; mice; microbiota transfer ... See more keywords
Shotgun Metagenomics Study Suggests Alteration in Sulfur Metabolism and Oxidative Stress in Children with Autism and Improvement after Microbiota Transfer Therapy
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232113481
Abstract: Links between gut microbiota and autism spectrum disorder (ASD) have been explored in many studies using 16S rRNA gene amplicon and shotgun sequencing. Based on these links, microbiome therapies have been proposed to improve gastrointestinal… read more here.
Keywords: improvement; sulfur metabolism; microbiota; microbiota transfer ... See more keywords