Preformulation studies with phenylalanine ammonia lyase: essential prelude to a microcapsule formulation for the management of phenylketonuria.
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DOI: 10.1016/j.xphs.2022.03.016
Abstract: Phenylalanine ammonia lyase (PAL) metabolizes phenylalanine to transcinnamic acid (TCA). Our eventual goal is to develop a PAL microcapsule formulation to deplete phenylalanine in the gastrointestinal tract (g.i.t). The focus of this research is pre-formulation… read more here.
Keywords: formulation; ammonia lyase; phenylalanine ammonia; microcapsule formulation ... See more keywords