Capillary and microchip electrophoresis method development for amino acid monitoring during biopharmaceutical cultivation
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DOI: 10.1002/biot.202100325
Abstract: The increased use of biopharmaceuticals calls for improved means of bioprocess monitoring. In this work, capillary electrophoresis (CE) and microchip electrophoresis (MCE) methods were developed and applied for the analysis of amino acids (AAs) in… read more here.
Keywords: microchip electrophoresis; cultivation; analysis; amino ... See more keywords
Rapid quantification of quinine by multi‐stacking in a portable microchip electrophoresis system
Sign Up to like & getrecommendations! Published in 2019 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201800398
Abstract: A new multi‐stacking pre‐concentration procedure based on field‐enhanced sample injection (FESI), field‐amplified sample stacking, and transient isotachophoresis was developed and implemented in a compact microchip electrophoresis (MCE) with a double T‐junction glass chip, coupled with… read more here.
Keywords: multi stacking; system; microchip electrophoresis; electrophoresis ... See more keywords
Method development for mono- and disaccharides monitoring in cell culture medium by capillary and microchip electrophoresis.
Sign Up to like & getrecommendations! Published in 2021 at "Electrophoresis"
DOI: 10.1002/elps.202100213
Abstract: The rapidly growing, competitive biopharmaceutical market requires tight bioprocess monitoring. An integrated, automated platform for the routine on-line/ at-line monitoring of key factors in the cell culture medium could greatly improve process monitoring. Mono- and… read more here.
Keywords: microchip electrophoresis; cell culture; electrophoresis; monitoring ... See more keywords
Fast determination of paracetamol and its hydrolytic degradation product p-aminophenol by capillary and microchip electrophoresis with contactless conductivity detection.
Sign Up to like & getrecommendations! Published in 2021 at "Electrophoresis"
DOI: 10.1002/elps.202100347
Abstract: Paracetamol (PAC) is one of the most extensively used analgesics and antipyretic drugs to treat mild and moderate pain. P-aminophenol (PAP), the main hydrolytic degradation product of PAC, can be found in environmental water. Recently,… read more here.
Keywords: microchip electrophoresis; electrophoresis; detection; hydrolytic degradation ... See more keywords
Concepts and recent advances in microchip electrophoresis coupled to mass spectrometry: Technologies and applications
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DOI: 10.1002/elps.202200179
Abstract: The online coupling of microchip electrophoresis (ME) as a fast, highly efficient, and low‐cost miniaturized separation technique to mass spectrometry (MS) as an information‐rich and sensitive characterization technique results in ME–MS an attractive tool for… read more here.
Keywords: mass spectrometry; concepts recent; microchip electrophoresis; electrophoresis ... See more keywords
Fast analysis of domoic acid using microchip electrophoresis with laser-induced fluorescence detection.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of separation science"
DOI: 10.1002/jssc.201600982
Abstract: A fast and effective method was developed to detect domoic acid based upon microchip electrophoresis combined with laser-induced fluorescence detection. Through study of the gated injection process on the cross channel of the microchip, the… read more here.
Keywords: detection; microchip electrophoresis; induced fluorescence; domoic acid ... See more keywords
Sensitivity enhancing injection from a sample reservoir and channel interface in microchip electrophoresis.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of separation science"
DOI: 10.1002/jssc.201601064
Abstract: The stacking of a cationic analyte (i.e., rhodamine B) at the interface between a sample reservoir and channel in a microchip electrophoresis device is described for the first time. Stacking at negative polarity was by… read more here.
Keywords: channel; interface; microchip electrophoresis; injection ... See more keywords
A novel multiplex signal amplification strategy based on microchip electrophoresis platform for the improved separation and detection of microRNAs.
Sign Up to like & getrecommendations! Published in 2018 at "Talanta"
DOI: 10.1016/j.talanta.2018.07.037
Abstract: A multiplex fluorescence signal amplification method based on microchip electrophoresis (MCE) platform was developed for the improvements in the separation and detection of microRNAs. The method used two kinds of fluorescein amidite labeled DNA signal… read more here.
Keywords: detection; microchip electrophoresis; based microchip; platform ... See more keywords