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Published in 2019 at "Nature Methods"
DOI: 10.1038/s41592-019-0395-x
Abstract: In 2013 we established a cryo-electron microscopy (cryo-EM) technique called microcrystal electron diffraction (MicroED). Since that time, data collection and analysis schemes have been fine-tuned, and structures for more than 40 different proteins, oligopeptides and…
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Keywords:
technique;
microcrystal electron;
diffraction microed;
electron diffraction ... See more keywords
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Published in 2021 at "RSC Advances"
DOI: 10.1039/d1ra03100g
Abstract: Therapeutic options in response to the coronavirus disease 2019 (COVID-19) outbreak are urgently needed. In this communication, we demonstrate how to support selection of a stable solid form of an antiviral drug remdesivir in quick…
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Keywords:
form;
solid form;
electron diffraction;
microcrystal electron ... See more keywords
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Published in 2020 at "IUCrJ"
DOI: 10.1107/s205225252000072x
Abstract: Serial X-ray crystallography and microcrystal electron diffraction were performed using microcrystals of the enzyme cyclophilin A. The results highlight the strengths and weakness of the two complementary methods.
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Keywords:
microcrystal electron;
crystallography microcrystal;
serial ray;
ray crystallography ... See more keywords