Mutagenesis and structural modeling implicate RME-8 IWN domains as conformational control points
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Genetics"
DOI: 10.1101/2022.06.16.496522
Abstract: After endocytosis, transmembrane cargo is differentially sorted into degradative or recycling pathways. This process is facilitated by recruitment into physically distinct degradative or recycling microdomains on the limiting membrane of individual endosomes. Endosomal sorting complexes… read more here.
Keywords: rme; dnaj domain; iwn domains; microdomain ... See more keywords
Extracellular Calcium Influx Pathways in Astrocyte Calcium Microdomain Physiology
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DOI: 10.3390/biom11101467
Abstract: Astrocytes are complex glial cells that play many essential roles in the brain, including the fine-tuning of synaptic activity and blood flow. These roles are linked to fluctuations in intracellular Ca2+ within astrocytes. Recent advances… read more here.
Keywords: microdomain; extracellular calcium; physiology; ca2 ... See more keywords