High proportions of PD-1+ and PD-L1+ leukocytes in classical Hodgkin lymphoma microenvironment are associated with inferior outcome.
Sign Up to like & getrecommendations! Published in 2017 at "Blood advances"
DOI: 10.1182/bloodadvances.2017006346
Abstract: Immune checkpoint inhibition targeting the programmed death receptor (PD)-1 pathway is a novel treatment approach in relapsed and refractory classical Hodgkin lymphoma (cHL). Identifying patients with a high risk of treatment failure could support the… read more here.
Keywords: microenvironment; high proportions; microenvironment associated; hodgkin lymphoma ... See more keywords
Immune Gene Signatures and Immunotypes in Immune Microenvironment Are Associated With Glioma Prognose
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.823910
Abstract: Glioma is the most common primary malignant brain tumor in adults with very poor prognosis. The limited new therapeutic strategies for glioma patients can be partially attributed to the complex tumor microenvironment. However, knowledge about… read more here.
Keywords: microenvironment associated; microenvironment; immune microenvironment; immune response ... See more keywords