In situ microenvironment remodeling using a dual-responsive system: photodegradable hydrogels and gene activation by visible light.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm00617k
Abstract: A 3D microenvironment with dynamic cell-biomaterial interactions was developed using a dual-responsive system for in situ microenvironment remodeling and control of cellular function. A visible-light-responsive polymer was utilized to prepare a hydrogel with photodegradation properties,… read more here.
Keywords: system; situ microenvironment; dual responsive; medicine ... See more keywords
Multikinase Inhibition Induces Tumor Microenvironment Remodeling in PDAC.
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DOI: 10.1158/2159-8290.cd-rw2022-026
Abstract: Combination trametinib and nintedanib induces cell death and reprograms the immunosuppressive microenvironment. read more here.
Keywords: tumor microenvironment; inhibition induces; remodeling pdac; multikinase inhibition ... See more keywords
The Regulatory Effect of SIRT1 on Extracellular Microenvironment Remodeling
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.52619
Abstract: The sirtuins family is well known by its unique nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase function. The most-investigated member of the family, Sirtuin 1 (SIRT1), accounts for deacetylating a broad range of transcription factors and coregulators,… read more here.
Keywords: microenvironment; regulatory effect; extracellular microenvironment; effect sirt1 ... See more keywords