Multidimensional spatial characterization of the tumor microenvironment (TME) in synchronous melanoma metastases (SMM) to yield insights into mixed responses to therapy in metastatic melanoma (MM) patients (pts).
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.9575
Abstract: 9575Background: Although both targeted and immune therapies have significantly improved outcomes for mm pts, only a minority of pts experience durable responses with many pts with multiple SMM demo... read more here.
Keywords: melanoma; multidimensional spatial; microenvironment tme; tumor microenvironment ... See more keywords
Exploring the tumor microenvironment (TME) in patients with mismatch repair-deficient (MMRd) endometrial cancer (EC) undergoing immune checkpoint inhibitor (ICI) therapy: Proteomic insights into immune resistance mechanisms.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2024.42.16_suppl.5609
Abstract: 5609 Background: MMRd status is a robust predictive biomarker for ICI in EC, however half of these pts do not respond. Most studies exploring biomarkers of response to ICI have focused on tumor or immune… read more here.
Keywords: microenvironment tme; tumor microenvironment; tumor; organization ... See more keywords