Articles with "microenvironmental changes" as a keyword



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Abstract 4644: Modeling the effects of niche specific microenvironmental changes on patient-derived organoids

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-4644

Abstract: Here, we present an approach to study the effects of microenvironmental changes on inter- and intratumoral heterogeneity using colorectal cancer (CRC) patient-derived organoids. We identified relevant paracrine interactions between stromal and tumor cells based on… read more here.

Keywords: microenvironmental changes; niche specific; derived organoids; colorectal cancer ... See more keywords