Major basic protein and eosinophil peroxidase support microfilariae motility inhibition by eosinophil ETosis
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DOI: 10.1371/journal.pntd.0012889
Abstract: Eosinophils are a hallmark of filarial infections. They are primary effector cells and can attack filariae by releasing extracellular traps that contain toxic cationic proteins, such as eosinophil peroxidase and major basic protein. Previous studies… read more here.
Keywords: major basic; motility; microfilariae; eosinophil peroxidase ... See more keywords
Repeated sensitization of mice with microfilariae of Litomosoides sigmodontis induces pulmonary eosinophilia in an IL-33-dependent manner
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DOI: 10.1371/journal.ppat.1012071
Abstract: Background Eosinophilia is a hallmark of helminth infections and eosinophils are essential in the protective immune responses against helminths. Nevertheless, the distinct role of eosinophils during parasitic filarial infection, allergy and autoimmune disease-driven pathology is… read more here.
Keywords: mice; lung; pathology; pulmonary eosinophilia ... See more keywords