Recreating Physiological Environments In Vitro: Design Rules for Microfluidic-Based Vascularized Tissue Constructs.
Sign Up to like & getrecommendations! Published in 2020 at "Small"
DOI: 10.1002/smll.201905055
Abstract: Vascularization of engineered tissue constructs remains one of the greatest unmet challenges to mimicking the native tissue microenvironment in vitro. The main obstacle is recapitulating the complexity of the physiological environment while providing simplicity in… read more here.
Keywords: microfluidic based; microenvironment; recreating physiological; tissue ... See more keywords
Microfluidic-based liquid-liquid microextraction in combination with smartphone-based on-chip detection for the determination of copper in biological, environmental, and food samples
Sign Up to like & getrecommendations! Published in 2021 at "Microchemical Journal"
DOI: 10.1016/j.microc.2020.105655
Abstract: Abstract In the present work, a simple and green microfluidic-based liquid-liquid microextraction in combination with smartphone-based on-chip detection was introduced for the determination of copper in environmental, biological, and food samples. The procedure was based… read more here.
Keywords: microfluidic based; detection; smartphone; determination ... See more keywords
Microfluidic-Based Synthesis of Magnetic Nanoparticles Coupled with Miniaturized NMR for Online Relaxation Studies.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b02374
Abstract: Using compact desktop NMR systems for rapid characterization of relaxation properties directly after synthesis can expedite the development of functional magnetic nanoparticles. Therefore, an automated system that combines a miniaturized NMR relaxometer and a flow-based… read more here.
Keywords: microfluidic based; based synthesis; relaxation; magnetic nanoparticles ... See more keywords
Development of a Microfluidic-Based Post-Treatment Process for Size-Controlled Lipid Nanoparticles and Application to siRNA Delivery.
Sign Up to like & getrecommendations! Published in 2020 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.0c05489
Abstract: Microfluidic methodologies for preparation of lipid nanoparticles (LNPs) based on an organic solvent injection method enable precise size control of the LNPs. After preparation of LNPs, the organic solvent injection method needs some post-treatments, such… read more here.
Keywords: microfluidic based; post treatment; size; post ... See more keywords
Microfluidic-Based Cell-Embedded Microgels Using Nonfluorinated Oil as a Model for the Gastrointestinal Niche.
Sign Up to like & getrecommendations! Published in 2018 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.7b16916
Abstract: Microfluidic-based cell encapsulation has promising potential in therapeutic applications. It also provides a unique approach for studying cellular dynamics and interactions, though this concept has not yet been fully explored. No in vitro model currently… read more here.
Keywords: microfluidic based; microgels using; model; using nonfluorinated ... See more keywords
Elucidating the Determinants of Polymerase Specificity by Microfluidic-Based Deep Mutational Scanning.
Sign Up to like & getrecommendations! Published in 2019 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.9b00104
Abstract: Engineering polymerases to synthesize artificial genetic polymers with unique backbone structures is limited by a general lack of understanding about the structural determinants that govern substrate specificity. Here, we report a high-throughput microfluidic-based approach for… read more here.
Keywords: deep mutational; microfluidic based; polymerase specificity; mutational scanning ... See more keywords
Wearable microfluidic-based e-skin sweat sensors
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d1ra07888g
Abstract: Electronic skins (e-skins) are soft (deformable and stretchable) state-of-the-art wearable devices that emulate the attributes of human skin and act as a Human–Machine Interface (HMI). Recent advances in e-skin for real-time detection of medical signals… read more here.
Keywords: skin sweat; wearable microfluidic; microfluidic based; sweat sensors ... See more keywords
Genetic interaction mapping with microfluidic-based single cell sequencing
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0171302
Abstract: Genetic interaction mapping is useful for understanding the molecular basis of cellular decision making, but elucidating interactions genome-wide is challenging due to the massive number of gene combinations that must be tested. Here, we demonstrate… read more here.
Keywords: single cell; microfluidic based; genetic interaction; interaction ... See more keywords
Evaluation of bacterial proliferation with a microfluidic-based device: Antibiochip
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0223932
Abstract: The measurement of the proliferation (and the relevant inhibition of proliferation) of microbes is used in different settings, from industry to laboratory medicine. Thus, in this study, the capacity of the Antibiochip (ELTEK spa), a… read more here.
Keywords: microfluidic based; antibiochip; based device; evaluation bacterial ... See more keywords
Microfluidic-Based Detection of AML-Specific Biomarkers Using the Example of Promyelocyte Leukemia
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21238942
Abstract: A microfluidic assay for the detection of promyelocytic leukemia (PML)-retinoic acid receptor α (RARα) fusion protein was developed. This microfluidic-based system can be used for rapid personalized differential diagnosis of acute promyelocyte leukemia (APL) with… read more here.
Keywords: microfluidic based; rar; detection; promyelocyte leukemia ... See more keywords
Microfluidic-Based Technologies for CTC Isolation: A Review of 10 Years of Intense Efforts towards Liquid Biopsy
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23041981
Abstract: The selection of circulating tumor cells (CTCs) directly from blood as a real-time liquid biopsy has received increasing attention over the past ten years, and further analysis of these cells may greatly aid in both… read more here.
Keywords: based technologies; microfluidic based; ctc isolation; isolation ... See more keywords