Portable Battery-Driven Microfluidic Cell Separation Instrument with Multiple Operational Modes.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c03833
Abstract: Current microfluidic cell separation instruments are commonly bulky, expensive, and inconvenient for use in resource-limited environments. Herein, we developed a low-cost, portable, battery-driven microfluidic cell separation instrument by integrating a microfluidic separator, a low-cost gas-driven… read more here.
Keywords: cell; separation instrument; cell separation; microfluidic cell ... See more keywords
Inhibition of AURKA kinase activity suppresses collective invasion in a microfluidic cell culture platform
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-02623-1
Abstract: Tumor local invasion is the first step of metastasis cascade which remains the key obstacle for cancer therapy. Collective cell migration plays a critical role in tumor invading into surrounding tissues. In vitro assays fail… read more here.
Keywords: invasion; microfluidic cell; inhibition aurka; collective invasion ... See more keywords
Measuring Single-Cell Phenotypic Growth Heterogeneity Using a Microfluidic Cell Volume Sensor
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-36000-3
Abstract: An imaging-integrated microfluidic cell volume sensor was used to evaluate the volumetric growth rate of single cells from a Saccharomyces cerevisiae population exhibiting two phenotypic expression states of the PDR5 gene. This gene grants multidrug… read more here.
Keywords: microfluidic cell; volume sensor; cell; cell volume ... See more keywords
Clog-free high-throughput microfluidic cell isolation with multifunctional microposts
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-94123-6
Abstract: Microfluidics have been applied to filtration of rare tumor cells from the blood as liquid biopsies. Processing is highly limited by low flow rates and device clogging due to a single function of fluidic paths.… read more here.
Keywords: microfluidic cell; clog free; cancer cells; free high ... See more keywords
A Microfluidic Cell Co-Culture Chip for the Monitoring of Interactions between Macrophages and Fibroblasts
Sign Up to like & getrecommendations! Published in 2022 at "Biosensors"
DOI: 10.3390/bios13010070
Abstract: Macrophages and fibroblasts are two types of important cells in wound healing. The development of novel platforms for studying the interrelationship between these two cells is crucial for the exploration of wound-healing mechanisms and drug… read more here.
Keywords: culture; macrophages fibroblasts; wound healing; microfluidic cell ... See more keywords